SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q1JIS1

- G6PI_STRPD

UniProt

Q1JIS1 - G6PI_STRPD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glucose-6-phosphate isomerase

Gene
pgi, MGAS10270_Spy0187
Organism
Streptococcus pyogenes serotype M2 (strain MGAS10270)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei291 – 2911Proton donor By similarity
Active sitei312 – 3121 By similarity
Active sitei426 – 4261 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciSPYO370552:GHYF-234-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:MGAS10270_Spy0187
OrganismiStreptococcus pyogenes serotype M2 (strain MGAS10270)
Taxonomic identifieri370552 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002436: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 449449Glucose-6-phosphate isomeraseUniRule annotationPRO_0000252652Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi370552.MGAS10270_Spy0187.

Structurei

3D structure databases

ProteinModelPortaliQ1JIS1.
SMRiQ1JIS1. Positions 3-449.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiKNMTHIT.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1JIS1-1 [UniParc]FASTAAdd to Basket

« Hide

MSHITFDYSK VLESFAGQHE IDFLQGQVTE ADKLLREGTG PGSDFLGWLD    50
LPENYDKEEF ARILTAAEKI KADSEVLVVI GIGGSYLGAK AAIDFLNHHF 100
ANLQTAKERK APQILYAGNS ISSTYLADLV EYVQDKEFSV NVISKSGTTT 150
EPAIAFRVFK ELLVKKYGQE EANKRIYATT DKVKGAVKVE ADANNWETFV 200
VPDNVGGRFS VLTAVGLLPI AASGADITAL MEGANAAHKD LSSDKISENI 250
AYQYAAVRNV LYRKGYITEI LANYEPSLQY FGEWWKQLAG ESEGKDQKGI 300
YPTSANFSTD LHSLGQFIQE GYRNLFETVI RVDNPRKNVI IPELAEDLDG 350
LGYLQGKDVD FVNKKATDGV LLAHTDGGVP NMFVTLPAQD EFTLGYTIYF 400
FELAIAVSGY MNAVNPFDQP GVEAYKRNMF ALLGKPGFEA LSAELNARL 449
Length:449
Mass (Da):49,448
Last modified:June 13, 2006 - v1
Checksum:iC27EF520241AB422
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000260 Genomic DNA. Translation: ABF33252.1.
RefSeqiYP_597796.1. NC_008022.1.

Genome annotation databases

EnsemblBacteriaiABF33252; ABF33252; MGAS10270_Spy0187.
GeneIDi4063526.
KEGGisph:MGAS10270_Spy0187.
PATRICi19718241. VBIStrPyo120482_0188.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000260 Genomic DNA. Translation: ABF33252.1 .
RefSeqi YP_597796.1. NC_008022.1.

3D structure databases

ProteinModelPortali Q1JIS1.
SMRi Q1JIS1. Positions 3-449.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 370552.MGAS10270_Spy0187.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABF33252 ; ABF33252 ; MGAS10270_Spy0187 .
GeneIDi 4063526.
KEGGi sph:MGAS10270_Spy0187.
PATRICi 19718241. VBIStrPyo120482_0188.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi KNMTHIT.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci SPYO370552:GHYF-234-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus."
    Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R., Musser J.M.
    Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MGAS10270.

Entry informationi

Entry nameiG6PI_STRPD
AccessioniPrimary (citable) accession number: Q1JIS1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: June 13, 2006
Last modified: June 11, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi