SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q1JHV9

- Q1JHV9_STRPD

UniProt

Q1JHV9 - Q1JHV9_STRPD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, MGAS10270_Spy0499
Organism
Streptococcus pyogenes serotype M2 (strain MGAS10270)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei155 – 1551 By similarityUniRule annotation
Active sitei600 – 6001 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciSPYO370552:GHYF-550-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:MGAS10270_Spy0499Imported
OrganismiStreptococcus pyogenes serotype M2 (strain MGAS10270)Imported
Taxonomic identifieri370552 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002436: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi370552.MGAS10270_Spy0499.

Structurei

3D structure databases

ProteinModelPortaliQ1JHV9.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiELSTISC.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1JHV9-1 [UniParc]FASTAAdd to Basket

« Hide

MVKSGMIEET SKEGDGHLPL KKLESSNNQA IIAEEVALLK EMLENITRRM    50
IGDDAFTVIE SIVVLSEKQD YIELEKVVAN ISNQEMEVIS RYFSILPLLI 100
NISEDVDLAY EINHQNNTDT DYLGKLALTI KDLAGKDNGK DILEQVNVVP 150
VLTAHPTQVQ RKTILELTTH IHKLLRKYRD AKAGVINLEK WRQELYRYIE 200
MIMQTDIIRE KKLQVKNEIK NVMQYYDGSL IQAVTKLTTE YKNLAQKHGL 250
ELDNPKPITM GMWIGGDRDG NPFVTAETLC LSATVQSEVI LNYYIDKLAA 300
LYRTFSLSST LVQPNSEVER LASLSQDQSI YRGNEPYRRA FHYIQSRLKQ 350
TQIQLTNQPA ARMSSSVGLS TSAWSSPASL ENPILAYDSP VDFKADLKAI 400
EQSLLDNGNS ALIEGDLREV MQAVDIFGFF LASIDMRQDS SVQEACVAEL 450
LKGANIVDDY SSLSETEKCD VLVQQLMEEP RTLSSAAVAK SDLLEKELAI 500
YTTARELKDK LGEEVIKQHI ISHTESVSDM FELAIMLKEV GLVDQQRARV 550
QIVPLFETIE DLDNARDIMA AYLSHDIVKS WIATNRNYQE IMLGYSDSNK 600
DGGYLASGWT LYKAQNELTA IGEEHGVKIT FFHGRGGTVG RGGGPSYDAI 650
TSQPFGSIKD RIRLTEQGEI IENKYGNKDV AYYHLEMLIS ASINRMVTQM 700
ITDPNEIDSF REIMDSIVAD SNTIYRKLVF DNPHFYDYFF EASPIKEVSS 750
LNIGSRPAAR KTITEITGLR AIPWVFSWSQ NRIMFPGWYG VGSAFKRYID 800
RAQGNLERLQ HMYQTWPFFH SLLSNVDMVL SKSNMNIAFQ YAQLAESQDV 850
RDVFYEILDE WQLTKNVILA IQDHDDLLED NPSLKHSLKS RLPYFNVLNY 900
IQIELIKRWR NNQLDENDEK LIHTTINGIA TGLRNSG 937
Length:937
Mass (Da):106,395
Last modified:June 13, 2006 - v1
Checksum:i90025C0F2F3BC24A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000260 Genomic DNA. Translation: ABF33564.1.
RefSeqiYP_598108.1. NC_008022.1.

Genome annotation databases

EnsemblBacteriaiABF33564; ABF33564; MGAS10270_Spy0499.
GeneIDi4063881.
KEGGisph:MGAS10270_Spy0499.
PATRICi19718896. VBIStrPyo120482_0509.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000260 Genomic DNA. Translation: ABF33564.1 .
RefSeqi YP_598108.1. NC_008022.1.

3D structure databases

ProteinModelPortali Q1JHV9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 370552.MGAS10270_Spy0499.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABF33564 ; ABF33564 ; MGAS10270_Spy0499 .
GeneIDi 4063881.
KEGGi sph:MGAS10270_Spy0499.
PATRICi 19718896. VBIStrPyo120482_0509.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238647.
KOi K01595.
OMAi ELSTISC.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci SPYO370552:GHYF-550-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus."
    Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R., Musser J.M.
    Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MGAS10270Imported.

Entry informationi

Entry nameiQ1JHV9_STRPD
AccessioniPrimary (citable) accession number: Q1JHV9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi