Q1JH55 (Q1JH55_STRPD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hyaluronate lyase EMBL ABF33939.1
EC=4.2.2.1 EMBL ABF33939.1

Gene names

Name:	hylA EMBL ABF33939.1
Ordered Locus Names:	MGAS10270_Spy0874

Organism

Streptococcus pyogenes serotype M2 (strain MGAS10270) [Complete proteome] [HAMAP] EMBL ABF33939.1

Taxonomic identifier

370552 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	828 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL ABF33939.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro hyaluronate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1JH55 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: 69A91A72C72473B2	FASTA	828	95,519
	10 20 30 40 50 60 MVYFYLVNQS TFIISFLYWR NVSVNTYFCT HHKQLLLYSN LFLSFAMIGQ GTAIYADTLT 70 80 90 100 110 120 SNSEPNNTYF QTQTLTTTDS EKKVVQPQQK DYYTELLDQW NSIIAGNDAY DKTNPDMVTF 130 140 150 160 170 180 HNKAEKDAQN IIKSYQGPDH ENRTYLWEHA KDYSASTNIT KTYRNIEKIA KQITNPESCY 190 200 210 220 230 240 YQDSKAIAIV KDGMAFMYEH AYNLNRENHQ TTGKENKENW WVYEIGTPRA INNTLSLMYP 250 260 270 280 290 300 YFTQEEILKY TAPIEKFVPD PTRFRVRAAN FSPFEANSGN LIDMGRVKLI SGILRKDDLE 310 320 330 340 350 360 ISDTIKAIEK VFTLVDEGNG FYQDGSLIDH VVTNTQSPLY KKGIAYTGAY GNVLIDGLSQ 370 380 390 400 410 420 LIPIIQKTKS PIEADKMATI YHWINHSFFP IIVRGEMMDM TRGRSISRFN AQSHVAGIEA 430 440 450 460 470 480 LRAILRIADM SEEPHRLELK TRIKTLVTQG NAFYNVYDNL KTYHDIKLMK ELLSDTSVPV 490 500 510 520 530 540 QKLDSYVASF NSMDKLALYN NKHDFAFGLS MFSNRTQNYE AMNNENLHGW FTSDGMFYLY 550 560 570 580 590 600 NNDLGHYSEN YWATVNPYRL PGTTETEQKP LEGTPENIKT NYQQVGMTSL SDDAFVASKK 610 620 630 640 650 660 LNNTSALAAM TFTNWNKSLT LNKGWFILGN KIIFVGSNIK NQSSHKAYTT IEQRKENQKH 670 680 690 700 710 720 PYCSYVNNQP VDLNNQLVDF TNTKSIFLES DDPAQNIGYY FFKPRTLSIS KALQTGKWQN 730 740 750 760 770 780 IKADDKSPEA IKEVSNTFIT IMQNHTQEGD RYAYMMLPNM TRQEFETYIS KLDIDLLENN 790 800 810 820 DKLAAVYDHD SQQMHVIHYE KKATMFSNHN LSHQGFYSFP HPVKQNQQ

References

[1]

"Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus." Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R., Musser J.M. Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006) [PubMed: 16636287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000260 Genomic DNA. Translation: ABF33939.1.
RefSeq	YP_598483.1. NC_008022.1.
3D structure databases
ProteinModelPortal	Q1JH55.
SMR	Q1JH55. Positions 90-803.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1JH55.
Protein family/group databases
CAZy	PL8. Polysaccharide Lyase Family 8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000040750; EBSTRP00000039234; EBSTRG00000040747.
GeneID	4063587.
GenomeReviews	Gene locus MGAS10270_Spy0874 in contig CP000260_GR.
KEGG	sph:MGAS10270_Spy0874.
PATRIC	19719664. VBIStrPyo120482_0889.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG04835.
GeneTree	EBGT00050000027679.
HOGENOM	HBG698564.
OMA	TKTYRNI.
ProtClustDB	CLSK442844.
Enzyme and pathway databases
BioCyc	SPYO370552:MGAS10270_SPY0874-MONOMER.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
KO	K01727.
Pfam	PF02278. Lyase_8. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF74650. Gal_mut_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1JH55_STRPD

Accession

Primary (citable) accession number: Q1JH55

Entry history

Integrated into UniProtKB/TrEMBL:	June 13, 2006
Last sequence update:	June 13, 2006
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)