ID   Q1JGD8_STRPD            Unreviewed;       474 AA.
AC   Q1JGD8;
DT   13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2006, sequence version 1.
DT   27-MAR-2024, entry version 85.
DE   SubName: Full=Beta-glucosidase {ECO:0000313|EMBL:ABF34206.1};
DE            EC=3.2.1.21 {ECO:0000313|EMBL:ABF34206.1};
GN   Name=bglA2 {ECO:0000313|EMBL:ABF34206.1};
GN   OrderedLocusNames=MGAS10270_Spy1141 {ECO:0000313|EMBL:ABF34206.1};
OS   Streptococcus pyogenes serotype M2 (strain MGAS10270).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=370552 {ECO:0000313|EMBL:ABF34206.1, ECO:0000313|Proteomes:UP000002436};
RN   [1] {ECO:0000313|EMBL:ABF34206.1, ECO:0000313|Proteomes:UP000002436}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGAS10270 {ECO:0000313|EMBL:ABF34206.1,
RC   ECO:0000313|Proteomes:UP000002436};
RX   PubMed=16636287; DOI=10.1073/pnas.0510279103;
RA   Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R.,
RA   Musser J.M.;
RT   "Molecular genetic anatomy of inter- and intraserotype variation in the
RT   human bacterial pathogen group A Streptococcus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 1 family.
CC       {ECO:0000256|RuleBase:RU003690}.
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DR   EMBL; CP000260; ABF34206.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q1JGD8; -.
DR   CAZy; GH1; Glycoside Hydrolase Family 1.
DR   KEGG; sph:MGAS10270_Spy1141; -.
DR   HOGENOM; CLU_001859_0_1_9; -.
DR   Proteomes; UP000002436; Chromosome.
DR   GO; GO:0008422; F:beta-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102483; F:scopolin beta-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR   PANTHER; PTHR10353:SF36; KLOTHO (MAMMALIAN AGING-ASSOCIATED PROTEIN) HOMOLOG; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 1.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:ABF34206.1};
KW   Hydrolase {ECO:0000313|EMBL:ABF34206.1}.
FT   REGION          19..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   474 AA;  54106 MW;  E794740F898B0F21 CRC64;
     MSKERTKDMK QRKHRYQFPD GFLWGSSTSG PQSEGTVPGD GKGPSNWDYW FSIESAKFHH
     QIGPEKTSTF YENYKGDIAL LKETGHTIFR TSIQWSRLIP EGVGEVNPKA VTFYREVFQD
     IIAQGIKLIV NLYHFDLPYA LQEKGGWENK ATVWAYETYA KTCFELFGDL VNTWITFNEP
     IVPVECGYLG YYHYPCKVDA KAAVQVAYNT QLASSLAVKA CHKLHPDHKI SIVLNMTPAY
     PRSNAPEDVK AARIAELFQT KSFLDPSVLG VYPAELVSIL EEADLLPQYS ADELEIIKNN
     TVDFLGVNYY QPLRVQAPSK SQQEGDPLIL DIYFEPYDMP GKKVNPHRGW EIYEPGLYDI
     ALNLKEHYGN IEWLVTENGM GVEGEEAFLA DGQIQDDYRI TFIEDHLIQL HKALGEGANC
     KGYLLWTFID CWSWLNAYKN RYGLVALDLE SQKRTIKKSG YWFKALSESN GFDK
//