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Protein

Exodeoxyribonuclease 7 small subunit

Gene

xseB

Organism
Streptococcus pyogenes serotype M2 (strain MGAS10270)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 small subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII small subunitUniRule annotation
Short name:
Exonuclease VII small subunitUniRule annotation
Gene namesi
Name:xseBUniRule annotation
Ordered Locus Names:MGAS10270_Spy1248
OrganismiStreptococcus pyogenes serotype M2 (strain MGAS10270)
Taxonomic identifieri370552 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000002436 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003037581 – 71Exodeoxyribonuclease 7 small subunitAdd BLAST71

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1JG31.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XseB family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000228798.
KOiK03602.
OMAiKLTRECQ.

Family and domain databases

Gene3Di1.10.287.1040. 1 hit.
HAMAPiMF_00337. Exonuc_7_S. 1 hit.
InterProiView protein in InterPro
IPR003761. Exonuc_VII_S.
PANTHERiPTHR34137. PTHR34137. 1 hit.
PfamiView protein in Pfam
PF02609. Exonuc_VII_S. 1 hit.
PIRSFiPIRSF006488. Exonuc_VII_S. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD028235. Exonuc_VII_S. 1 hit.
TIGRFAMsiTIGR01280. xseB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1JG31-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKTKTFEEN LQDLETIVNK LENGDVPLEE AISEFQKGML LSKELQKTLQ
60 70
AAEKTLVKVM QADGTEVDMD D
Length:71
Mass (Da):7,988
Last modified:June 13, 2006 - v1
Checksum:iF472577D43021AE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000260 Genomic DNA. Translation: ABF34313.1.
RefSeqiWP_002983901.1. NZ_CVUH01000008.1.

Genome annotation databases

EnsemblBacteriaiABF34313; ABF34313; MGAS10270_Spy1248.
GeneIDi13902456.
KEGGisph:MGAS10270_Spy1248.
PATRICi19720430. VBIStrPyo120482_1272.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000260 Genomic DNA. Translation: ABF34313.1.
RefSeqiWP_002983901.1. NZ_CVUH01000008.1.

3D structure databases

ProteinModelPortaliQ1JG31.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABF34313; ABF34313; MGAS10270_Spy1248.
GeneIDi13902456.
KEGGisph:MGAS10270_Spy1248.
PATRICi19720430. VBIStrPyo120482_1272.

Phylogenomic databases

HOGENOMiHOG000228798.
KOiK03602.
OMAiKLTRECQ.

Family and domain databases

Gene3Di1.10.287.1040. 1 hit.
HAMAPiMF_00337. Exonuc_7_S. 1 hit.
InterProiView protein in InterPro
IPR003761. Exonuc_VII_S.
PANTHERiPTHR34137. PTHR34137. 1 hit.
PfamiView protein in Pfam
PF02609. Exonuc_VII_S. 1 hit.
PIRSFiPIRSF006488. Exonuc_VII_S. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD028235. Exonuc_VII_S. 1 hit.
TIGRFAMsiTIGR01280. xseB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEX7S_STRPD
AccessioniPrimary (citable) accession number: Q1JG31
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: June 13, 2006
Last modified: April 12, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.