Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ferredoxin--NADP reductase

Gene

MGAS2096_Spy0727

Organism
Streptococcus pyogenes serotype M12 (strain MGAS2096)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei35FADUniRule annotation1
Binding sitei43FADUniRule annotation1
Binding sitei48FADUniRule annotation1
Binding sitei90FAD; via amide nitrogen and carbonyl oxygenUniRule annotation1
Binding sitei123FAD; via amide nitrogenUniRule annotation1
Binding sitei285FADUniRule annotation1
Binding sitei326FADUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandFAD, Flavoprotein, NADP

Names & Taxonomyi

Protein namesi
Recommended name:
Ferredoxin--NADP reductaseUniRule annotation (EC:1.18.1.2UniRule annotation)
Short name:
FNRUniRule annotation
Short name:
Fd-NADP(+) reductaseUniRule annotation
Gene namesi
Ordered Locus Names:MGAS2096_Spy0727
OrganismiStreptococcus pyogenes serotype M12 (strain MGAS2096)
Taxonomic identifieri370553 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003649631 – 330Ferredoxin--NADP reductaseAdd BLAST330

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1JCC9
SMRiQ1JCC9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ferredoxin--NADP reductase type 2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000072909
KOiK21567
OMAiCGFHEAT
OrthoDBiPOG091H07EY

Family and domain databases

Gene3Di3.50.50.60, 3 hits
HAMAPiMF_01685 FENR2, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR023753 FAD/NAD-binding_dom
IPR022890 Fd--NADP_Rdtase_type_2
IPR000103 Pyridine_nuc-diS_OxRdtase_2
PfamiView protein in Pfam
PF07992 Pyr_redox_2, 1 hit
PRINTSiPR00469 PNDRDTASEII
SUPFAMiSSF51905 SSF51905, 1 hit

Sequencei

Sequence statusi: Complete.

Q1JCC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDKAYDITI IGGGPIGLFA AFYAGLRGVT VKIIESLSEL GGQPAILYPE
60 70 80 90 100
KMIYDIPAYP SLTGVELTEN LIKQLSRFED RTTICLKEEV LTFDKVKGGF
110 120 130 140 150
SIRTNKAEHF SKAIIIACGN GAFAPRTLGL ESEENFADHN LFYNVHQLDQ
160 170 180 190 200
FAGQKVVICG GGDSAVDWAL ALEDIAESVT VVHRRDAFRA HEHSVELLKT
210 220 230 240 250
STVNLLTPYV PKALKGIGNL AEKLVIQKVK EDEVLELELD SLIVSFGFST
260 270 280 290 300
SNKNLKNWNL DYKRSSITVS PLFQTSQEGI FAIGDAAAYN GKVDLIATGF
310 320 330
GEAPTAVNQA INYIYPDRDN RVVHSTSLID
Length:330
Mass (Da):36,148
Last modified:June 13, 2006 - v1
Checksum:iEECC6544A10319DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000261 Genomic DNA Translation: ABF35779.1

Genome annotation databases

EnsemblBacteriaiABF35779; ABF35779; MGAS2096_Spy0727
KEGGispj:MGAS2096_Spy0727

Similar proteinsi

Entry informationi

Entry nameiFENR_STRPB
AccessioniPrimary (citable) accession number: Q1JCC9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: June 13, 2006
Last modified: March 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health