Q1J6X4 (Q1J6X4_STRPF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hyaluronate lyase EMBL ABF37859.1
EC=4.2.2.1 EMBL ABF37859.1

Gene names

Name:	hylA EMBL ABF37859.1
Ordered Locus Names:	MGAS10750_Spy0909

Organism

Streptococcus pyogenes serotype M4 (strain MGAS10750) [Complete proteome] [HAMAP] EMBL ABF37859.1

Taxonomic identifier

370554 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	868 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL ABF37859.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro hyaluronate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1J6X4 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: CF8827D36B425327	FASTA	868	99,733
	10 20 30 40 50 60 MNTYFCTHHK QLLLYSNLFL SFAMMGQGTA IYADTLTSNS KPNNTYFQTQ TLTTTDSEKK 70 80 90 100 110 120 VVQPQQKDYY TELLDQWNSI IAGNDAYDKT NPDMVTFHNK AEKDAQNIIK SYQEPDHENR 130 140 150 160 170 180 TYLWEHAKDY SASANITKTY RNIEKIAKQI TNPESCYYQD SKAIAIVKDG MAFMYEHAYN 190 200 210 220 230 240 LDRENHQTTG KENKENWWDY EIGTPRAINN TLSLMYPYFT QEEILKYTAP IEKFVPDPTR 250 260 270 280 290 300 FRVRAANFPP FEANSGNLID MGRVKLISGI LRKDDLEISD TIKAIEKVFT LVDEGNGFYQ 310 320 330 340 350 360 DGSLIDHVVT NAQSPLYKKG IAYTGAYGNV LIDGLSQLIP IIQKTKSPIE ADKMATIYHW 370 380 390 400 410 420 INHSFFPIIV RGEMMDMTRG RSISRFNAQS HVAGIEALRA ILRIADMSEE PHRLALKTRI 430 440 450 460 470 480 KTLVTQGNVF YNVYDNLKTY HDIKLMKELL SDTSVPVQKL DSYVASFNSM DKLALYNNKH 490 500 510 520 530 540 DFAFGLSMFS NRTQNYEAMN NENLHGWFTS DGMFYLYNND LGHYSENYWA TVNPYRLPGT 550 560 570 580 590 600 TETEQKPLEG TPENIKTNYQ QVGMTSLSDD AFVASKKLNN TSALAAMTFT NWNKSLTLNK 610 620 630 640 650 660 GWFILGNKII FVGSNIKNQS SHKAYTTIEQ RKENQKHPYC SYVNNQPVDL NNQLVDFTNT 670 680 690 700 710 720 KSIFLESDDP AQNIGYYFFK PTTLSISKAL QTGKWQNIKA DDKSPEAIKE VSNTFITIMQ 730 740 750 760 770 780 NHTQDGDRYA YMMLPNMTRQ EFETYISKLD IDLLENNDKL AAVYDHDSQQ MHVIHYEKKA 790 800 810 820 830 840 TTFSNHNLSH QGFYSFPHPV KQNQQQKLAH QGIAAKNNAL NSHKIPHKRQ RRLPRTGYQS 850 860 SSLEFLGGAL VASFNHITKP FRKKDLRI

References

[1]

"Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus." Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R., Musser J.M. Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006) [PubMed: 16636287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000262 Genomic DNA. Translation: ABF37859.1.
RefSeq	YP_602403.1. NC_008024.1.
3D structure databases
ProteinModelPortal	Q1J6X4.
SMR	Q1J6X4. Positions 67-784.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1J6X4.
Protein family/group databases
CAZy	PL8. Polysaccharide Lyase Family 8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000042347; EBSTRP00000040742; EBSTRG00000042342.
GeneID	4066928.
GenomeReviews	Gene locus MGAS10750_Spy0909 in contig CP000262_GR.
KEGG	spi:MGAS10750_Spy0909.
PATRIC	19728076. VBIStrPyo25933_0933.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG04835.
GeneTree	EBGT00050000027679.
HOGENOM	HBG698564.
OMA	TKTYRNI.
ProtClustDB	CLSK442844.
Enzyme and pathway databases
BioCyc	SPYO370554:MGAS10750_SPY0909-MONOMER.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
KO	K01727.
Pfam	PF02278. Lyase_8. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF74650. Gal_mut_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1J6X4_STRPF

Accession

Primary (citable) accession number: Q1J6X4

Entry history

Integrated into UniProtKB/TrEMBL:	June 13, 2006
Last sequence update:	June 13, 2006
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)