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Protein
Submitted name:

16S rRNA m(5)C 967 methyltransferase

Gene

sunL

Organism
Streptococcus pyogenes serotype M4 (strain MGAS10750)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei280S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei308S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei327S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei380NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotationImported, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
16S rRNA m(5)C 967 methyltransferaseImported (EC:2.1.1.-Imported)
Gene namesi
Name:sunLImported
Ordered Locus Names:MGAS10750_Spy1446Imported
OrganismiStreptococcus pyogenes serotype M4 (strain MGAS10750)Imported
Taxonomic identifieri370554 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000002434 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ1J5J0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini168 – 439SAM_MT_RSMB_NOPInterPro annotationAdd BLAST272

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.
OrthoDBiPOG091H02E2.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1J5J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADNWKKSTR GKALLVIEAI FDQGAYTNIA LNQQLSSKAL SAKDRALLTE
60 70 80 90 100
IVYGTVSRKI SLEWYLAHYV KDRDKLDKWV YYLLMLSLYQ LIYLDKLPAH
110 120 130 140 150
AIVNDAVGIA KNRGNKKGAE KFVNAILRQF TSHPLPDMET IKRRNKYYSV
160 170 180 190 200
KYSLPVWLVK KLEDQFGSDR AVAIMESLFM RSKASTRVTD PLKLEEVAEA
210 220 230 240 250
LDAERSLLSA TGLTKASGHF AASDYFTNGD ITIQDESSQL VAPTLNIDGD
260 270 280 290 300
DIILDACSAP GGKTSHIASY LKTGKVIALD LYDHKLELVK ENANRLGVAD
310 320 330 340 350
NIETRKLDAR EVHRHFEKDS FDKILVDAPC SGIGLIRRKP DIKYNKESQD
360 370 380 390 400
FNALQAIQLE ILSSVCQTLR KGGIITYSTC TIFDEENRQV IEAFLQSHPN
410 420 430 440
FEQVKLNHTQ ADIVKDGYLI ITPEQYQTDG FFIGQVRRVL
Length:440
Mass (Da):49,602
Last modified:June 13, 2006 - v1
Checksum:iC95EE70174B1DD0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000262 Genomic DNA. Translation: ABF38396.1.
RefSeqiWP_011528856.1. NC_008024.1.

Genome annotation databases

EnsemblBacteriaiABF38396; ABF38396; MGAS10750_Spy1446.
KEGGispi:MGAS10750_Spy1446.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ1J5J0_STRPF
AccessioniPrimary (citable) accession number: Q1J5J0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: June 7, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported