Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphate acetyltransferase

Gene

pta

Organism
Deinococcus geothermalis (strain DSM 11300)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in acetate metabolism.By similarity

Catalytic activityi

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathwayi: acetyl-CoA biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes acetyl-CoA from acetate.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Acetate kinase (ackA)
  2. Phosphate acetyltransferase (pta)
This subpathway is part of the pathway acetyl-CoA biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes acetyl-CoA from acetate, the pathway acetyl-CoA biosynthesis and in Metabolic intermediate biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00340; UER00459

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate acetyltransferase (EC:2.3.1.8)
Alternative name(s):
Phosphotransacetylase
Gene namesi
Name:pta
Ordered Locus Names:Dgeo_0051
OrganismiDeinococcus geothermalis (strain DSM 11300)
Taxonomic identifieri319795 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002431 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004055451 – 703Phosphate acetyltransferaseAdd BLAST703

Proteomic databases

PRIDEiQ1J2D0

Interactioni

Protein-protein interaction databases

STRINGi319795.Dgeo_0051

Structurei

3D structure databases

ProteinModelPortaliQ1J2D0
SMRiQ1J2D0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni377 – 703Phosphate acetyltransferaseAdd BLAST327

Domaini

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site (By similarity).By similarity

Sequence similaritiesi

In the N-terminal section; belongs to the CobB/CobQ family.Curated
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.Curated

Phylogenomic databases

eggNOGiENOG4105C6K Bacteria
COG0280 LUCA
COG0857 LUCA
HOGENOMiHOG000053797
KOiK13788
OMAiTPLMFEY
OrthoDBiPOG091H01MW

Family and domain databases

Gene3Di3.40.1390.20, 1 hit
InterProiView protein in InterPro
IPR010766 DRTGG
IPR016475 P-Actrans_bac
IPR027417 P-loop_NTPase
IPR004614 P_AcTrfase
IPR002505 PTA_PTB
IPR028979 Ser_kin/Pase_Hpr-like_N_sf
PfamiView protein in Pfam
PF07085 DRTGG, 1 hit
PF01515 PTA_PTB, 1 hit
PIRSFiPIRSF006107 PhpActrans_proteobac, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF75138 SSF75138, 1 hit
TIGRFAMsiTIGR00651 pta, 1 hit

Sequencei

Sequence statusi: Complete.

Q1J2D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTLFIAPTR NGVGLTSTAL GLLRALERQG LKVAFLKPIA QTHEAAPDDS
60 70 80 90 100
VHWARTLAHA VTPDPILLSV AEEQLSQGQE EELMENVVAL AREAAAGVTG
110 120 130 140 150
GADVLVVEGL ALNERNVYAG PLNASLARNL EADVVLVSSL AGVTPATLAD
160 170 180 190 200
ELEIAAQAYR RSDGSGLAGY VLNFAPLELD FGGLLADLRA RSRILASGEL
210 220 230 240 250
PLLGVIAQSP TLAAPRTLDV ARHLGAEVLN EGEARLRRVT STVVTARSVP
260 270 280 290 300
KMADLFTSGA LVVTPGDRED VVMAAALSHL SGVPLAGLLF TSGSTPEAAI
310 320 330 340 350
ERLCRAALTS TLPVLRVETN SYNTASRLSR MEARVPHDDL ERMERTLDFI
360 370 380 390 400
ADRLDTVPLG TRLRAPEGSE RRLPPSAFRY ELIQKARAAN KRIVLPEGDE
410 420 430 440 450
PRTVRAAIRC VEKGIARCVL LAQPEKVRQV AEGQGLTLPD GLEIIDPDRV
460 470 480 490 500
RANYVAPMVE LRKHKGLTAP QAEAQLEDNV VLGTMMLALD EVDGLVSGAV
510 520 530 540 550
HTTANTVRPA LQLIKTAPGV RLVSSIFFML MPEQVVVYGD AAINPNPNAE
560 570 580 590 600
ELADIAIQSA DSARAFGIPP RIAMLSYSTG ESGAGADVEK VRIATRLVRE
610 620 630 640 650
RRPDLPVDGP LQYDAASVLS VGRQKAPNSP VAGRATVFIF PDLNTGNTTY
660 670 680 690 700
KAVQRAAGVV AVGPMLQGLR KPVNDLSRGA LVDDIVYTIA LTAIQATQAR

EGA
Length:703
Mass (Da):74,708
Last modified:June 13, 2006 - v1
Checksum:iB27D3B9DC99BD169
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000359 Genomic DNA Translation: ABF44354.1
RefSeqiWP_011529201.1, NC_008025.1

Genome annotation databases

EnsemblBacteriaiABF44354; ABF44354; Dgeo_0051
KEGGidge:Dgeo_0051

Similar proteinsi

Entry informationi

Entry nameiPTA_DEIGD
AccessioniPrimary (citable) accession number: Q1J2D0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: June 13, 2006
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health