Q1IZ55 (FABZ_DEIGD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Short name=(3R)-hydroxymyristoyl ACP dehydrase
EC=4.2.1.-

Gene names

Name:	fabZ
Ordered Locus Names:	Dgeo_1182

Organism

Deinococcus geothermalis (strain DSM 11300) [Complete proteome] [HAMAP]

Taxonomic identifier

319795 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length	142 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in saturated fatty acids biosynthesis By similarity. HAMAP MF_00406
Subcellular location	Cytoplasm By similarity HAMAP MF_00406.
Sequence similarities	Belongs to the thioester dehydratase family. FabZ subfamily.

Ontologies

Keywords
Biological process	Lipid A biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: InterPro lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydro-lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 142	142	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase HAMAP MF_00406		PRO_0000340773
Sites
	Active site	49	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1IZ55 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: ACBD5733F12CBE4A	FASTA	142	15,487
	10 20 30 40 50 60 MEPLLIQDVL KTLPHRFPFV LVDRVLSAQD GEVHALKNVT VNEPFFPGHF PQEPVMPGVL 70 80 90 100 110 120 IVEALAQASM FCLHGQLEPG TVGYLAGVEG ARFKRKVIPG DQLHLYAKLD FLRRGLGKTT 130 140 CRAEVDGQVA AEATILFAVA KG

References

[1]

"Complete sequence of chromosome 1 of Deinococcus geothermalis DSM 11300." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Daly M.J., Fredrickson J.K., Makarova K.S., Gaidamakova E.K., Zhai M., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 11300.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000359 Genomic DNA. Translation: ABF45479.1.
RefSeq	YP_604648.1. NC_008025.1.
3D structure databases
ProteinModelPortal	Q1IZ55.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1IZ55.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4058798.
GenomeReviews	Gene locus Dgeo_1182 in contig CP000359_GR.
KEGG	dge:Dgeo_1182.
NMPDR	fig|68909.1.peg.2060.
PATRIC	21624251. VBIDeiGeo41128_1762.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0764.
HOGENOM	HBG433282.
OMA	GVIGIMS.
PhylomeDB	Q1IZ55.
ProtClustDB	PRK00006.
Enzyme and pathway databases
BioCyc	DGEO319795:DGEO_1182-MONOMER.
Family and domain databases
HAMAP	MF_00406. FabZ. [Tree]
InterPro	IPR013114. FabA_FabZ. IPR010084. FabZ. [Graphical view]
KO	K02372.
Pfam	PF07977. FabA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01750. FabZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FABZ_DEIGD

Accession

Primary (citable) accession number: Q1IZ55

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	June 13, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program