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Protein

Chaperone protein ClpB

Gene

clpB

Organism
Deinococcus geothermalis (strain DSM 11300)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ChaperoneUniRule annotationSAAS annotation

Keywords - Biological processi

Stress responseUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciDGEO319795:GHMU-1232-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein ClpBUniRule annotation
Gene namesi
Name:clpBUniRule annotation
Ordered Locus Names:Dgeo_1210Imported
OrganismiDeinococcus geothermalis (strain DSM 11300)Imported
Taxonomic identifieri319795 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
ProteomesiUP000002431 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homohexamer. The oligomerization is ATP-dependent (By similarity).SAAS annotation
Homohexamer; The oligomerization is ATP-dependent.UniRule annotation

Protein-protein interaction databases

STRINGi319795.Dgeo_1210.

Structurei

3D structure databases

ProteinModelPortaliQ1IZ27.
SMRiQ1IZ27. Positions 13-847.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili405 – 43329UniRule annotationAdd
BLAST
Coiled coili441 – 50060UniRule annotationAdd
BLAST
Coiled coili506 – 53429UniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ClpA/ClpB family.UniRule annotation

Keywords - Domaini

Coiled coilUniRule annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiCOG0542.
HOGENOMiHOG000218211.
KOiK03695.
OMAiCEKEANK.
OrthoDBiEOG65F8SM.

Family and domain databases

Gene3Di1.10.1780.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR017730. Chaperonin_ClpB.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR001270. ClpA/B.
IPR018368. ClpA/B_CS1.
IPR028299. ClpA/B_CS2.
IPR023150. Dbl_Clp-N.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 2 hits.
PF10431. ClpB_D2-small. 1 hit.
[Graphical view]
PRINTSiPR00300. CLPPROTEASEA.
SMARTiSM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR03346. chaperone_ClpB. 1 hit.
PROSITEiPS00870. CLPAB_1. 1 hit.
PS00871. CLPAB_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1IZ27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAIEEEITL NPERFTEAAL QAIAQAQQLA QANQQQTLTV AHVLRALLDN
60 70 80 90 100
DTAARALSAA GGNLQAIRQA LDAEIAKLPR VQGGGEQLYL DPALNRALQG
110 120 130 140 150
AEKQAQTLGD AFIAADTLLL ALRAESRTPG LPSAAALQQA VTEARKGKTV
160 170 180 190 200
TTKTAEQQFD ALEKYGTDLT QRARDGKFDP VIGRDEEIRR VMQILLRRTK
210 220 230 240 250
NNPVLIGEPG VGKTAIVEGL AIRIVKGDVP EGLKNKRIVS LDMGSLLAGA
260 270 280 290 300
KFRGEFEERL KAVIEEVVQS AGEVILFVDE LHTIVGAGKT EGSPDAGNML
310 320 330 340 350
KPALARGELH MIGATTLSEY REIEKDPALE RRFQPVFVDE PSVEDTISIL
360 370 380 390 400
RGIKEKYQAH HNVNLTDPAL VAAAQLSHRY ITDRQLPDKA IDLIDEAAAR
410 420 430 440 450
LRMALESSPE RIDQLERRKL QLEIEREALK KEKDVDSQNR LLDIEDQLKA
460 470 480 490 500
ITDELAEVRS RWEAERQEVQ ALREKRDQLD QVRTEIEKAR REYDLGKAAQ
510 520 530 540 550
LEYGTLPQLE KDVQELERKL KAAEFAHMEV TDEDIASVVS RWTGIPVSKL
560 570 580 590 600
MEGEREKLLR LEEQLHERVI GQDRAIVSVA DAIRRARAGL NDPNRPLGSF
610 620 630 640 650
MFLGPTGVGK TELAKALAEF LFDSPDAMIR IDMSEYMEKH SVARLIGAPP
660 670 680 690 700
GYVGYEEGGQ LTEAVRRRPY SVILLDEIEK AHPDVFNVLL QVLDDGRLTD
710 720 730 740 750
GQGRTVDFRN TLIIMTSNIG SHLILEAQAR GDSPESIREQ VLQVLQAHFR
760 770 780 790 800
PEFLNRIDDI IVFDALTPAN LHKIVEIQLG GLRRRLAERR VTLHLTDAAK
810 820 830 840 850
DKLAQIGYDP AFGARPLKRV IAREIETPLA REILQGRVPE GSTLTVDYDG
860
NQFRFETGVL N
Length:861
Mass (Da):95,751
Last modified:June 13, 2006 - v1
Checksum:i4108BE718892B60C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000359 Genomic DNA. Translation: ABF45507.1.

Genome annotation databases

EnsemblBacteriaiABF45507; ABF45507; Dgeo_1210.
KEGGidge:Dgeo_1210.
PATRICi21624309. VBIDeiGeo41128_1791.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000359 Genomic DNA. Translation: ABF45507.1.

3D structure databases

ProteinModelPortaliQ1IZ27.
SMRiQ1IZ27. Positions 13-847.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi319795.Dgeo_1210.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABF45507; ABF45507; Dgeo_1210.
KEGGidge:Dgeo_1210.
PATRICi21624309. VBIDeiGeo41128_1791.

Phylogenomic databases

eggNOGiCOG0542.
HOGENOMiHOG000218211.
KOiK03695.
OMAiCEKEANK.
OrthoDBiEOG65F8SM.

Enzyme and pathway databases

BioCyciDGEO319795:GHMU-1232-MONOMER.

Family and domain databases

Gene3Di1.10.1780.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR017730. Chaperonin_ClpB.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR001270. ClpA/B.
IPR018368. ClpA/B_CS1.
IPR028299. ClpA/B_CS2.
IPR023150. Dbl_Clp-N.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 2 hits.
PF10431. ClpB_D2-small. 1 hit.
[Graphical view]
PRINTSiPR00300. CLPPROTEASEA.
SMARTiSM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR03346. chaperone_ClpB. 1 hit.
PROSITEiPS00870. CLPAB_1. 1 hit.
PS00871. CLPAB_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 11300Imported.

Entry informationi

Entry nameiQ1IZ27_DEIGD
AccessioniPrimary (citable) accession number: Q1IZ27
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: July 22, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.