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Protein

Chaperone protein ClpB

Gene

clpB

Organism
Deinococcus geothermalis (strain DSM 11300)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation
Biological processStress responseUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein ClpBUniRule annotation
Gene namesi
Name:clpBUniRule annotation
Ordered Locus Names:Dgeo_1210Imported
OrganismiDeinococcus geothermalis (strain DSM 11300)Imported
Taxonomic identifieri319795 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002431 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homohexamer. The oligomerization is ATP-dependent.SAAS annotation
Homohexamer; The oligomerization is ATP-dependent.UniRule annotation

Protein-protein interaction databases

STRINGi319795.Dgeo_1210

Structurei

3D structure databases

ProteinModelPortaliQ1IZ27
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini199 – 343AAAInterPro annotationAdd BLAST145
Domaini596 – 748AAAInterPro annotationAdd BLAST153
Domaini766 – 855ClpB_D2-smallInterPro annotationAdd BLAST90

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili405 – 432UniRule annotationAdd BLAST28
Coiled coili441 – 499UniRule annotationAdd BLAST59
Coiled coili506 – 533UniRule annotationAdd BLAST28

Sequence similaritiesi

Belongs to the ClpA/ClpB family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilUniRule annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C2Z Bacteria
COG0542 LUCA
HOGENOMiHOG000218211
KOiK03695
OMAiHHKVRIK
OrthoDBiPOG091H019M

Family and domain databases

Gene3Di1.10.1780.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR017730 Chaperonin_ClpB
IPR019489 Clp_ATPase_C
IPR004176 Clp_N
IPR036628 Clp_N_dom_sf
IPR001270 ClpA/B
IPR018368 ClpA/B_CS1
IPR028299 ClpA/B_CS2
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF07724 AAA_2, 1 hit
PF02861 Clp_N, 2 hits
PF10431 ClpB_D2-small, 1 hit
PRINTSiPR00300 CLPPROTEASEA
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SM01086 ClpB_D2-small, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
SSF81923 SSF81923, 1 hit
TIGRFAMsiTIGR03346 chaperone_ClpB, 1 hit
PROSITEiView protein in PROSITE
PS00870 CLPAB_1, 1 hit
PS00871 CLPAB_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q1IZ27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAIEEEITL NPERFTEAAL QAIAQAQQLA QANQQQTLTV AHVLRALLDN
60 70 80 90 100
DTAARALSAA GGNLQAIRQA LDAEIAKLPR VQGGGEQLYL DPALNRALQG
110 120 130 140 150
AEKQAQTLGD AFIAADTLLL ALRAESRTPG LPSAAALQQA VTEARKGKTV
160 170 180 190 200
TTKTAEQQFD ALEKYGTDLT QRARDGKFDP VIGRDEEIRR VMQILLRRTK
210 220 230 240 250
NNPVLIGEPG VGKTAIVEGL AIRIVKGDVP EGLKNKRIVS LDMGSLLAGA
260 270 280 290 300
KFRGEFEERL KAVIEEVVQS AGEVILFVDE LHTIVGAGKT EGSPDAGNML
310 320 330 340 350
KPALARGELH MIGATTLSEY REIEKDPALE RRFQPVFVDE PSVEDTISIL
360 370 380 390 400
RGIKEKYQAH HNVNLTDPAL VAAAQLSHRY ITDRQLPDKA IDLIDEAAAR
410 420 430 440 450
LRMALESSPE RIDQLERRKL QLEIEREALK KEKDVDSQNR LLDIEDQLKA
460 470 480 490 500
ITDELAEVRS RWEAERQEVQ ALREKRDQLD QVRTEIEKAR REYDLGKAAQ
510 520 530 540 550
LEYGTLPQLE KDVQELERKL KAAEFAHMEV TDEDIASVVS RWTGIPVSKL
560 570 580 590 600
MEGEREKLLR LEEQLHERVI GQDRAIVSVA DAIRRARAGL NDPNRPLGSF
610 620 630 640 650
MFLGPTGVGK TELAKALAEF LFDSPDAMIR IDMSEYMEKH SVARLIGAPP
660 670 680 690 700
GYVGYEEGGQ LTEAVRRRPY SVILLDEIEK AHPDVFNVLL QVLDDGRLTD
710 720 730 740 750
GQGRTVDFRN TLIIMTSNIG SHLILEAQAR GDSPESIREQ VLQVLQAHFR
760 770 780 790 800
PEFLNRIDDI IVFDALTPAN LHKIVEIQLG GLRRRLAERR VTLHLTDAAK
810 820 830 840 850
DKLAQIGYDP AFGARPLKRV IAREIETPLA REILQGRVPE GSTLTVDYDG
860
NQFRFETGVL N
Length:861
Mass (Da):95,751
Last modified:June 13, 2006 - v1
Checksum:i4108BE718892B60C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000359 Genomic DNA Translation: ABF45507.1

Genome annotation databases

EnsemblBacteriaiABF45507; ABF45507; Dgeo_1210
KEGGidge:Dgeo_1210

Similar proteinsi

Entry informationi

Entry nameiQ1IZ27_DEIGD
AccessioniPrimary (citable) accession number: Q1IZ27
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: May 23, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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