Q1IYS0 (COMB_DEIGD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	Dgeo_1318

Organism

Deinococcus geothermalis (strain DSM 11300) [Complete proteome] [HAMAP]

Taxonomic identifier

319795 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000014465

Sequences

	Sequence		Length	Mass (Da)
	Q1IYS0 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: EE49938852EC8199	FASTA	241	24,721
	10 20 30 40 50 60 MRLRVDLLPH GNYPDVVLVV DVLRATTTAV TYLERGADAL LLTATPEVAL GLRGAAGEGG 70 80 90 100 110 120 VLLGGERGGL PIPGFDFGNS PVEAAAQNFT GRVVVMNTTN GTGAAHIAAQ TGKHVLLAAL 130 140 150 160 170 180 TNAHAAARRA RALASEEIAI VCAGTDARVG LEDVYAAGVL AEYLLALGEF RIDDGARIAL 190 200 210 220 230 240 TIRRNAGDPL EALSSSGHGQ HLVGLGLGDD VRYAAQVSTS TVVPVLDATQ TTPEVLRFVG G

References

[1]

"Complete sequence of chromosome 1 of Deinococcus geothermalis DSM 11300." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Daly M.J., Fredrickson J.K., Makarova K.S., Gaidamakova E.K., Zhai M., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 11300.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000359 Genomic DNA. Translation: ABF45614.1.
RefSeq	YP_604783.1. NC_008025.1.
3D structure databases
ProteinModelPortal	Q1IYS0.
SMR	Q1IYS0. Positions 1-229.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1IYS0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4057088.
GenomeReviews	Gene locus Dgeo_1318 in contig CP000359_GR.
KEGG	dge:Dgeo_1318.
PATRIC	21624533. VBIDeiGeo41128_1903.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2045.
HOGENOM	HBG633644.
OMA	DFICSGY.
PhylomeDB	Q1IYS0.
ProtClustDB	PRK14100.
Enzyme and pathway databases
BioCyc	DGEO319795:DGEO_1318-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_DEIGD

Accession

Primary (citable) accession number: Q1IYS0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 13, 2006
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program