Reviewed, UniProtKB/Swiss-Prot Q1IY56 (KYNB_DEIGD)

Names and origin

Protein names

Recommended name:
    Kynurenine formamidase
      Short name=KFA
    EC=3.5.1.9
Alternative name(s):
    N-formylkynurenine formamidase

Gene names

Name:	kynB
Ordered Locus Names:	Dgeo_1533

Organism

Deinococcus geothermalis (strain DSM 11300) [Complete proteome] [HAMAP]

Taxonomic identifier

319795 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length	213 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine By similarity.
Catalytic activity	N-formyl-L-kynurenine + H2O = formate + L-kynurenine.
Pathway	Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.
Sequence similarities	Belongs to the kynB family.

Ontologies

Keywords
Biological process	Tryptophan catabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	anthranilate metabolic process Inferred from sequence or structural similarity. Source: UniProtKB tryptophan catabolic process to kynurenine Inferred from sequence or structural similarity. Source: UniProtKB
Molecular function	arylformamidase activity Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 213	213	Kynurenine formamidase		PRO_0000362121

Sequences

	Sequence		Length	Mass (Da)
	Q1IY56-1 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: F06679FFA4C5838C	FASTA	213	22,785
	10 20 30 40 50 60 MIDISRQLTP SHPNWPGDAP FRVKPGARIA QGDSVNTGEL CTSTHTGTHV DAPWHYSETG 70 80 90 100 110 120 ARLEEVELNR YVGRCRVVTV RAEGGLIPAA ALAGLPKRLP PRLLLHTGQP AHWTEFPEDF 130 140 150 160 170 180 AALDPALIRE AARRGVRLIG TDSPSVDPLT SKTLDAHHAC LETDTLILEG LNLAEVPDGE 190 200 210 YDLVCLPLPL AEVDGAPARA ILLPAGTLPE GEG

References

[1]

"Complete sequence of chromosome 1 of Deinococcus geothermalis DSM 11300." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Daly M.J., Fredrickson J.K., Makarova K.S., Gaidamakova E.K., Zhai M., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000359 Genomic DNA. Translation: ABF45828.1.
RefSeq	YP_604997.1.
3D structure databases
SMR	Q1IY56. Positions 1-203.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1IY56.
Genome annotation databases
GeneID	4057419.
GenomeReviews	Gene locus Dgeo_1533 in contig CP000359_GR.
KEGG	dge:Dgeo_1533.
NMPDR	fig|68909.1.peg.1683.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1878.
HOGENOM	HBG686791.
OMA	CPVNVGR.
Enzyme and pathway databases
BioCyc	DGEO319795:DGEO_1533-MONOMER.
Family and domain databases
InterPro	IPR007325. Cyclase. [Graphical view]
Pfam	PF04199. Cyclase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KYNB_DEIGD

Accession

Primary (citable) accession number: Q1IY56

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	June 13, 2006
Last modified:	January 19, 2010
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)