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Q1IW06

- KGUA_DEIGD

UniProt

Q1IW06 - KGUA_DEIGD

Protein

Guanylate kinase

Gene

gmk

Organism
Deinococcus geothermalis (strain DSM 11300)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (13 Jun 2006)
      Previous versions | rss
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    Functioni

    Essential for recycling GMP and indirectly, cGMP.UniRule annotation

    Catalytic activityi

    ATP + GMP = ADP + GDP.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi29 – 368ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. guanylate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. purine nucleotide metabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciDGEO319795:GHMU-2342-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
    Alternative name(s):
    GMP kinaseUniRule annotation
    Gene namesi
    Name:gmkUniRule annotation
    Ordered Locus Names:Dgeo_2284
    OrganismiDeinococcus geothermalis (strain DSM 11300)
    Taxonomic identifieri319795 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
    ProteomesiUP000002431: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 242242Guanylate kinasePRO_0000266316Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi319795.Dgeo_2284.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1IW06.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini22 – 200179Guanylate kinase-likeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the guanylate kinase family.UniRule annotation
    Contains 1 guanylate kinase-like domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0194.
    HOGENOMiHOG000037639.
    KOiK00942.
    OMAiMSHYNEY.
    OrthoDBiEOG6CP410.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    HAMAPiMF_00328. Guanylate_kinase.
    InterProiIPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00625. Guanylate_kin. 1 hit.
    [Graphical view]
    SMARTiSM00072. GuKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
    PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1IW06-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLPSMMVARP DPQTTSSSSH RGLLIVMTGA SGVGKGTLRE RWLAGQDVFY    50
    STSWTTREAR PGERDGVDYV FVTPEVFLEK VRQNGFLEHA QFVGNHYGTP 100
    TEPIEAALAR GQDVVLEIEV EGAMQVKERM GEEAVLVFIM PPSLTELRRR 150
    LTGRATETPE RIEKRLQRAR DEIMAAHAFR YVIVNDDLDR AVRELQAVQR 200
    AEHARQRPET EWTAEDRAAV QLAETVRSTV LTTEDLQRIV NS 242
    Length:242
    Mass (Da):27,315
    Last modified:June 13, 2006 - v1
    Checksum:i432B985A809849B4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000359 Genomic DNA. Translation: ABF46578.1.
    RefSeqiWP_011531398.1. NC_008025.1.
    YP_605747.1. NC_008025.1.

    Genome annotation databases

    EnsemblBacteriaiABF46578; ABF46578; Dgeo_2284.
    GeneIDi4059233.
    KEGGidge:Dgeo_2284.
    PATRICi21626571. VBIDeiGeo41128_2888.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000359 Genomic DNA. Translation: ABF46578.1 .
    RefSeqi WP_011531398.1. NC_008025.1.
    YP_605747.1. NC_008025.1.

    3D structure databases

    ProteinModelPortali Q1IW06.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 319795.Dgeo_2284.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABF46578 ; ABF46578 ; Dgeo_2284 .
    GeneIDi 4059233.
    KEGGi dge:Dgeo_2284.
    PATRICi 21626571. VBIDeiGeo41128_2888.

    Phylogenomic databases

    eggNOGi COG0194.
    HOGENOMi HOG000037639.
    KOi K00942.
    OMAi MSHYNEY.
    OrthoDBi EOG6CP410.

    Enzyme and pathway databases

    BioCyci DGEO319795:GHMU-2342-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    HAMAPi MF_00328. Guanylate_kinase.
    InterProi IPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00625. Guanylate_kin. 1 hit.
    [Graphical view ]
    SMARTi SM00072. GuKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR03263. guanyl_kin. 1 hit.
    PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 11300.

    Entry informationi

    Entry nameiKGUA_DEIGD
    AccessioniPrimary (citable) accession number: Q1IW06
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: June 13, 2006
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3