Reviewed, UniProtKB/Swiss-Prot Q1IV19 (GLMM_ACIBL)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Acid345_0276

Organism

Acidobacteria bacterium (strain Ellin345) [Complete proteome] [HAMAP]

Taxonomic identifier

204669 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Candidatus Koribacter

Protein attributes

Sequence length	463 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 463	463	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000305629
Sites
	Active site	110	1	Phosphoserine intermediate By similarity
	Metal binding	110	1	Magnesium; via phosphate group By similarity
	Metal binding	255	1	Magnesium By similarity
	Metal binding	257	1	Magnesium By similarity
	Metal binding	259	1	Magnesium By similarity
Amino acid modifications
	Modified residue	110	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1IV19-1 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: FA6947AA9FD18FA0	FASTA	463	49,676
	10 20 30 40 50 60 MSLPTMDKPV RQLFGTDGIR GVAGEYPLDP HTVFAIGRAL GARLVEKYQT ARVLIGQDTR 70 80 90 100 110 120 ESSDWISRAL ARGLESANCG VASAGVITTP GVAYLTRTHG FSAGIVVSAS HNPWTDNGIK 130 140 150 160 170 180 VFGANGYKLS DDIEHEIEAQ IFYHLEELER AESEGEGPAM LPGDDKLRED YAEWLRSQVE 190 200 210 220 230 240 GTDFSKFRVL LDCANGAASS IAHLVFPKVG VFSEFTHICP TGRNINANCG ALHPEEAAKH 250 260 270 280 290 300 VGQSRGRFDL GITFDGDADR ALFSDGDGNI VNGDAVLLLA ARDMKARGHL KEDTVVATTM 310 320 330 340 350 360 SNMGLEAALK RSGIRMLRAA VGDKYVLEEM KKTGATLGGE QSGHILFMDS DATTGDGILT 370 380 390 400 410 420 ALRVLEVLAR SGKSLAELIA DLKVFPQVIR NVKVNAKIPM KELPAVMSAI EAAEQDLGDS 430 440 450 460 GRVVVRYSGT EKLARVMIEA ESEAKMNQHA TAIAEAIQEA IGI

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000360 Genomic DNA. Translation: ABF39281.1.
RefSeq	YP_589355.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1IV19.
Genome annotation databases
GeneID	4068820.
GenomeReviews	Gene locus Acid345_0276 in contig CP000360_GR.
KEGG	aba:Acid345_0276.
NMPDR	fig|204669.6.peg.268.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1IV19.
OMA	VHDRYIE.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_ACIBL

Accession

Primary (citable) accession number: Q1IV19

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	June 13, 2006
Last modified:	November 3, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)