Q1IUW9 (ARAA_KORVE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
L-arabinose isomerase
EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	Acid345_0326

Organism

Koribacter versatilis (strain Ellin345)

Taxonomic identifier

204669 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Candidatus Koribacter

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity. HAMAP MF_00519
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity. HAMAP MF_00519
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW fucose metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: EC L-fucose isomerase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	L-arabinose isomerase HAMAP MF_00519		PRO_0000259334
Sites
	Metal binding	306	1	Manganese By similarity
	Metal binding	333	1	Manganese By similarity
	Metal binding	349	1	Manganese By similarity
	Metal binding	448	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1IUW9 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: D833F08526172D9E	FASTA	500	55,218
	10 20 30 40 50 60 MIDLKKFEVW FVTGSQHLYG PETLEKVAEH SREIAGGLDA TPQMPVRVVF KPVLTTADAV 70 80 90 100 110 120 HELCREANNA AHCIGLVTWM HTFSPAKMWI AGLKALQKPF LHLHTQYNRE LPWATIDMDF 130 140 150 160 170 180 MNLNQAAHGD REFGFIGSRM RLDRKVVVGF WQDLEVISEL GTWARAAAGW HDAQHLKVAR 190 200 210 220 230 240 FGDNMRNVAV TEGDKVQAKI QLAYSVDGFG VGDLVARIHA ASDRDVDHLV SEYEDTYTLS 250 260 270 280 290 300 EPLTAKGKQR ASLLDAARIE LGLRHFLKDG NFHAFTDTFE DLHGLNQLPG IAVQRLMADG 310 320 330 340 350 360 YGFGAEGDWK TAALVRTMKV MAAGLDAGTS FMEDYTYHLE NGGLVLGAHM LEICPSIASG 370 380 390 400 410 420 KPSCEIHPLS IGGKGDPVRL VFDSQTGPAV VATIVDVGER FRMVINKVNV IPPEVPLPKL 430 440 450 460 470 480 PVARAVWIPE PNLAVAAACW IYAGGAHHTG FSLCLTAQHL QDYAEMAGIE CVLIDNDTTV 490 500 HACKNELRWN DAYYRLTGWR

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ellin345.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000360 Genomic DNA. Translation: ABF39331.1.
RefSeq	YP_589405.1. NC_008009.1.
3D structure databases
ProteinModelPortal	Q1IUW9.
SMR	Q1IUW9. Positions 1-496.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1IUW9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4070088.
GenomeReviews	Gene locus Acid345_0326 in contig CP000360_GR.
KEGG	aba:Acid345_0326.
NMPDR	fig|204669.6.peg.319.
PATRIC	31977384. VBICanKor57425_0346.
Phylogenomic databases
eggNOG	COG2160.
HOGENOM	HBG297198.
OMA	EVCPTIA.
PhylomeDB	Q1IUW9.
ProtClustDB	PRK02929.
Enzyme and pathway databases
BioCyc	ABAC204669:ACID345_0326-MONOMER.
Family and domain databases
HAMAP	MF_00519. Arabinose_Isome. [Tree]
InterPro	IPR024664. Ara_Isoase_C. IPR004216. Fuc/Ara_isomerase_C. IPR009015. Fucose_isomerase_N/cen. IPR003762. Lara_isomerase. [Graphical view]
KO	K01804.
Pfam	PF11762. Arabinose_Iso_C. 1 hit. PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF50443. Fuc_isomerase_C. 1 hit. SSF53743. Fuc_isomerase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAA_KORVE

Accession

Primary (citable) accession number: Q1IUW9

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	June 13, 2006
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program