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Q1IPW7 (UPPP_KORVE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Acid345_2082
OrganismKoribacter versatilis (strain Ellin345) [Reference proteome] [HAMAP]
Taxonomic identifier204669 [NCBI]
Taxonomic lineageBacteriaAcidobacteriaCandidatus Koribacter

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 286286Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000290674

Regions

Transmembrane43 – 6321Helical; Potential
Transmembrane91 – 11121Helical; Potential
Transmembrane118 – 13821Helical; Potential
Transmembrane150 – 17021Helical; Potential
Transmembrane189 – 20921Helical; Potential
Transmembrane236 – 25621Helical; Potential
Transmembrane264 – 28421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q1IPW7 [UniParc].

Last modified June 13, 2006. Version 1.
Checksum: 29948C2DDD70D44B

FASTA28631,183
        10         20         30         40         50         60 
MNAYLLAALL GVVEGLTEFL PVSSTAHLRI CEALLHIDLG DGFWKMFSIV IQLGAILCLP 

        70         80         90        100        110        120 
IYFRARISEF FATFPKGKSG NHTALTHPLT LTIIAFLCTA IPAFLFTKII GKHLESVIIM 

       130        140        150        160        170        180 
GSALLIGGIV MWIVDVMFAD KGATDDMDKM SVGQAIWIGL CQVLSAVFPG TSRSMSTIAA 

       190        200        210        220        230        240 
GQLSGMTRAA ALEFSFFLSI PTMVVATCYD LLKTLRHKDE AGAALGVVHM DAHAWITLAI 

       250        260        270        280 
GFIVSFIVAY FVVAWFMKWV RTRGFVPFAV YRIVVGIAVL AWALKR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000360 Genomic DNA. Translation: ABF41083.1.
RefSeqYP_591157.1. NC_008009.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204669.Acid345_2082.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABF41083; ABF41083; Acid345_2082.
GeneID4069933.
KEGGaba:Acid345_2082.
PATRIC31981152. VBICanKor57425_2214.

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycKVER204669:GHL8-2102-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_KORVE
AccessionPrimary (citable) accession number: Q1IPW7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: June 13, 2006
Last modified: February 19, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families