Q1IP39 (PSD_KORVE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

1. Phosphatidylserine decarboxylase alpha chain
2. Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	Acid345_2360

Organism

Koribacter versatilis (strain Ellin345)

Taxonomic identifier

204669 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Candidatus Koribacter

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664
Cofactor	Pyruvoyl group By similarity. HAMAP MF_00664
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	phosphatidylethanolamine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cofactor binding Inferred from electronic annotation. Source: InterPro phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 171	171	Phosphatidylserine decarboxylase beta chain By similarity		PRO_0000262177
	Chain	172 – 221	50	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_0000262178
Sites
	Site	171 – 172	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	172	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1IP39 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: C1D30B817FB240FE	FASTA	221	23,785
	10 20 30 40 50 60 MVRDGIYYVV AFVAVAILVG YFTIWPLAII PLLLAFFFGW FFRDPERQIP QTVGAIVSPG 70 80 90 100 110 120 DGKVTDIVTV DVNGEPRTRI SVFLNIFNVH VNRSPIAGTI REVRYQKGKF GNAMGAISAD 130 140 150 160 170 180 ANEQNIVTVE GEGQTVIFKQ IAGLLARRIV FTKKVGDVVG RGERVGLIKF GSRVDVIFTS 190 200 210 220 ESDVSVKIGD HVAGGSTILA VARVAHGNAP VLSGTERGGA R

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ellin345.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000360 Genomic DNA. Translation: ABF41361.1.
RefSeq	YP_591435.1. NC_008009.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1IP39.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4069172.
GenomeReviews	Gene locus Acid345_2360 in contig CP000360_GR.
KEGG	aba:Acid345_2360.
NMPDR	fig|204669.6.peg.2345.
PATRIC	31981748. VBICanKor57425_2511.
Phylogenomic databases
eggNOG	COG0688.
HOGENOM	HBG541103.
OMA	NERVVWH.
ProtClustDB	CLSK774759.
Enzyme and pathway databases
BioCyc	ABAC204669:ACID345_2360-MONOMER.
Family and domain databases
HAMAP	MF_00664. PS_decarb_type3. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR004428. PtdSer_deCO2ase-related. [Graphical view]
KO	K01613.
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00164. PS_decarb_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_KORVE

Accession

Primary (citable) accession number: Q1IP39

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	June 13, 2006
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program