Reviewed, UniProtKB/Swiss-Prot Q1INP0 (MURI_ACIBL)

Names and origin

Protein names

Recommended name:
    Glutamate racemase
    EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	Acid345_2509

Organism

Acidobacteria bacterium (strain Ellin345) [Complete proteome] [HAMAP]

Taxonomic identifier

204669 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Candidatus Koribacter

Protein attributes

Sequence length	291 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity.
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 291	291	Glutamate racemase HAMAP MF_00258		PRO_1000047538

Sequences

	Sequence		Length	Mass (Da)
	Q1INP0-1 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: 00AE70B892A8DB8D	FASTA	291	30,790
	10 20 30 40 50 60 MSRQRPVIGV FDSGFGGLTV LREIVRLVPN AEYLYFGDTA RLPYGTKSAD TVARYALGAC 70 80 90 100 110 120 HFLEGQGAEH LVIACNTATA LAMDAIEAKA NVPAIGVVEP GASAAAAISK TRSVAVIGTE 130 140 150 160 170 180 ATISSHAYHH ALERLGINAY EKATPLLVPL VEEGWTDHPV TKQVAEIYLQ DAFVRREQRS 190 200 210 220 230 240 DVLVLGCTHY PLIRPLLRKV VPSDVAIVDS AESTAKALAK KLGIAPPSAS AAGATQAAGA 250 260 270 280 290 RAQMAPSAPE PKEGTPDFRF FVTDSVQKFR RLGSGFLGHP VDNVEHVDLG G

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000360 Genomic DNA. Translation: ABF41510.1.
RefSeq	YP_591584.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1INP0.
Genome annotation databases
GeneID	4069878.
GenomeReviews	Gene locus Acid345_2509 in contig CP000360_GR.
KEGG	aba:Acid345_2509.
NMPDR	fig|204669.6.peg.2496.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1INP0.
OMA	VACNTAA.
Family and domain databases
HAMAP	MF_00258. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
TIGRFAMs	TIGR00067. glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_ACIBL

Accession

Primary (citable) accession number: Q1INP0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 13, 2006
Last modified:	November 3, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)