Q1INK7 (PGK_KORVE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglycerate kinase
EC=2.7.2.3

Gene names

Name:	pgk
Ordered Locus Names:	Acid345_2542

Organism

Koribacter versatilis (strain Ellin345)

Taxonomic identifier

204669 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Candidatus Koribacter

Protein attributes

Sequence length	403 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP MF_00145
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP MF_00145
Subunit structure	Monomer By similarity. HAMAP MF_00145
Subcellular location	Cytoplasm Potential HAMAP MF_00145.
Sequence similarities	Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycerate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 403	403	Phosphoglycerate kinase HAMAP MF_00145		PRO_1000057951
Regions
	Nucleotide binding	359 – 362	4	ATP By similarity
	Region	21 – 23	3	Substrate binding By similarity
	Region	60 – 63	4	Substrate binding By similarity
Sites
	Binding site	37	1	Substrate By similarity
	Binding site	125	1	Substrate By similarity
	Binding site	158	1	Substrate By similarity
	Binding site	209	1	ATP By similarity
	Binding site	332	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1INK7 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: ACB7645F453C68D0	FASTA	403	43,238
	10 20 30 40 50 60 MSKLSIKDLQ LSNKRVFMRV DFNVPLDENG RVTDDTRIRE TLPTIEYALR HGAKLILCSH 70 80 90 100 110 120 LGRPKGKPNP KMSLKPVAER LRVMLDHAIS PGQNVGFSPD CIGMQAQEMA KQLEKGQALL 130 140 150 160 170 180 LENVRFHAEE EKNDPAFAKE LASLCELYVN DAFGSAHRAH ASTEGITHYV EKSAAGLLMQ 190 200 210 220 230 240 KELDYLGKAT SNPAKPFVAI LGGAKVSDKI GVIQNLMAKV DAIIIGGGMA YTFLKAQGQE 250 260 270 280 290 300 IGKSLFEADK LDLAKQILAD AHKRGLKFLL PVDHVTADKF DMHATPHQIG EGQSIPAEQM 310 320 330 340 350 360 ALDIGPKTVA LFSEEIAKAR TIVWNGPMGV FEFDNFAKGT RAIAKAVAGN SGATSIVGGG 370 380 390 400 DSVAAVHDAG VADKITHIST GGGASLEFLE GKKLPGVEAL TNK

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ellin345.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000360 Genomic DNA. Translation: ABF41543.1.
RefSeq	YP_591617.1. NC_008009.1.
3D structure databases
ProteinModelPortal	Q1INK7.
SMR	Q1INK7. Positions 1-403.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1INK7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4072186.
GenomeReviews	Gene locus Acid345_2542 in contig CP000360_GR.
KEGG	aba:Acid345_2542.
NMPDR	fig|204669.6.peg.2531.
PATRIC	31982142. VBICanKor57425_2707.
Phylogenomic databases
eggNOG	COG0126.
HOGENOM	HBG453500.
OMA	DCIGDEV.
PhylomeDB	Q1INK7.
ProtClustDB	CLSK2467654.
Enzyme and pathway databases
BioCyc	ABAC204669:ACID345_2542-MONOMER.
Family and domain databases
HAMAP	MF_00145. Phosphoglyc_kinase. [Tree]
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. [Graphical view]
Gene3D	G3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit. G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
KO	K00927.
PANTHER	PTHR11406. PGK. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PIRSF	PIRSF000724. Pgk. 1 hit.
PRINTS	PR00477. PHGLYCKINASE.
SUPFAM	SSF53748. PGK. 1 hit.
PROSITE	PS00111. PGLYCERATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGK_KORVE

Accession

Primary (citable) accession number: Q1INK7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	June 13, 2006
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program