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Q1IK22

- KGUA_KORVE

UniProt

Q1IK22 - KGUA_KORVE

Protein

Guanylate kinase

Gene

gmk

Organism
Koribacter versatilis (strain Ellin345)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (13 Jun 2006)
      Previous versions | rss
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    • Comment

    Functioni

    Essential for recycling GMP and indirectly, cGMP.UniRule annotation

    Catalytic activityi

    ATP + GMP = ADP + GDP.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 178ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. guanylate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. purine nucleotide metabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciKVER204669:GHL8-3807-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
    Alternative name(s):
    GMP kinaseUniRule annotation
    Gene namesi
    Name:gmkUniRule annotation
    Ordered Locus Names:Acid345_3778
    OrganismiKoribacter versatilis (strain Ellin345)
    Taxonomic identifieri204669 [NCBI]
    Taxonomic lineageiBacteriaAcidobacteriaCandidatus Koribacter
    ProteomesiUP000002432: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 233233Guanylate kinasePRO_0000266280Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi204669.Acid345_3778.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1IK22.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini3 – 184182Guanylate kinase-likeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the guanylate kinase family.UniRule annotation
    Contains 1 guanylate kinase-like domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0194.
    HOGENOMiHOG000037638.
    KOiK00942.
    OMAiAGDLLEW.
    OrthoDBiEOG6CP410.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    HAMAPiMF_00328. Guanylate_kinase.
    InterProiIPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00625. Guanylate_kin. 1 hit.
    [Graphical view]
    SMARTiSM00072. GuKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
    PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1IK22-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSGTIFIISA PSGSGKSSLV NELRHVVPGL EFSISYTTRA PRGSEQNGRE    50
    YFFVTREKFD AMLAADEFLE HAEVFGECYG TAKHFVTEAL ARGNDLVLDI 100
    DVQGAAQLKV KLPDAVGIFI LPPSRKELEA RLKRRNLSDH VAPEVIERRL 150
    KGAGKEIENF SHYDYILVND NFETAVEQLR AIVLAERIRR SSTQISEENR 200
    AILEAAECCI RKNAMQRVQS ILDSFKDATD PQP 233
    Length:233
    Mass (Da):26,070
    Last modified:June 13, 2006 - v1
    Checksum:i7C714D51320A6B3B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000360 Genomic DNA. Translation: ABF42778.1.
    RefSeqiYP_592852.1. NC_008009.1.

    Genome annotation databases

    EnsemblBacteriaiABF42778; ABF42778; Acid345_3778.
    GeneIDi4071062.
    KEGGiaba:Acid345_3778.
    PATRICi31984804. VBICanKor57425_4031.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000360 Genomic DNA. Translation: ABF42778.1 .
    RefSeqi YP_592852.1. NC_008009.1.

    3D structure databases

    ProteinModelPortali Q1IK22.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 204669.Acid345_3778.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABF42778 ; ABF42778 ; Acid345_3778 .
    GeneIDi 4071062.
    KEGGi aba:Acid345_3778.
    PATRICi 31984804. VBICanKor57425_4031.

    Phylogenomic databases

    eggNOGi COG0194.
    HOGENOMi HOG000037638.
    KOi K00942.
    OMAi AGDLLEW.
    OrthoDBi EOG6CP410.

    Enzyme and pathway databases

    BioCyci KVER204669:GHL8-3807-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    HAMAPi MF_00328. Guanylate_kinase.
    InterProi IPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00625. Guanylate_kin. 1 hit.
    [Graphical view ]
    SMARTi SM00072. GuKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR03263. guanyl_kin. 1 hit.
    PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Ellin345.

    Entry informationi

    Entry nameiKGUA_KORVE
    AccessioniPrimary (citable) accession number: Q1IK22
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: June 13, 2006
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3