ID   Q1IJR6_KORVE            Unreviewed;       667 AA.
AC   Q1IJR6;
DT   13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2006, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ABF42884.1};
GN   OrderedLocusNames=Acid345_3884 {ECO:0000313|EMBL:ABF42884.1};
OS   Koribacter versatilis (strain Ellin345).
OC   Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC   Koribacter.
OX   NCBI_TaxID=204669 {ECO:0000313|EMBL:ABF42884.1, ECO:0000313|Proteomes:UP000002432};
RN   [1] {ECO:0000313|EMBL:ABF42884.1, ECO:0000313|Proteomes:UP000002432}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ellin345 {ECO:0000313|EMBL:ABF42884.1,
RC   ECO:0000313|Proteomes:UP000002432};
RX   PubMed=19201974; DOI=10.1128/AEM.02294-08;
RA   Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M.,
RA   Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B.,
RA   Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C.,
RA   Davidsen T.M., DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S.,
RA   Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P.,
RA   Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q.,
RA   Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R.,
RA   Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R.;
RT   "Three genomes from the phylum Acidobacteria provide insight into the
RT   lifestyles of these microorganisms in soils.";
RL   Appl. Environ. Microbiol. 75:2046-2056(2009).
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DR   EMBL; CP000360; ABF42884.1; -; Genomic_DNA.
DR   RefSeq; WP_011524683.1; NC_008009.1.
DR   AlphaFoldDB; Q1IJR6; -.
DR   STRING; 204669.Acid345_3884; -.
DR   EnsemblBacteria; ABF42884; ABF42884; Acid345_3884.
DR   KEGG; aba:Acid345_3884; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG4252; Bacteria.
DR   HOGENOM; CLU_000445_85_1_0; -.
DR   OrthoDB; 127505at2; -.
DR   Proteomes; UP000002432; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002432};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        14..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        353..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        378..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        405..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          468..602
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   667 AA;  73003 MW;  3B5F46812788F27F CRC64;
     MAAAPRKQSR AQRLFQRGAA LAAVFTAVLL IGVENTKPMR WLETGTYDAR MTWSLDPSRA
     DKSIVILDID NPSFEILKES FGRWPWTRMA WAGAIDYMAD GHPKVIAFDF KFGGSEDPKV
     DQAFAESIRS GRNVLLGFSF DPAQIEDVSD VKNRKLALLA RESLSDSHIL GEHFPPADQS
     LNVPLDILAK ASAGMGCLNA VYDDDGAVRR MPLGCNYGDL AFRTLDTRAV DYVRGHDASR
     FIRDGRYGDS TGERIPVDAN GHLLVWFHGR PHGTYERVPF WKLVCSAAPD SCPNLKEPIP
     PSYFKDKIVL VGASASGSFE LHSTPVGDAP GVFDRAAAID NLLHGEGILI APLWQHWILI
     AIMALVGWMV LTRLGVSVVG APVMLSILGV YAVLAAAVFR VEHLWLPMVS PLSAGALAYI
     SAGGVRYVTT GRELRATRHA LERHMSPQLA QYALEHGDNL AGERRELTIF FSDIRSFTTL
     TESLRDHPDK LLALLNEYLT AMCEVIFKYE GVVDKFIGDG ILAHWGAFTE GKNHALLAAQ
     ASLEMLDRLK QMNADWAAQG RDQLAIGIGL NTGEVTFGNV GAGQKTEFTV IGDPVNLASR
     LEGLNKEHHT SIIISEFTLE HLRGLVQTRE LGGVKVKGKT IETQIYELQG LATSQEPVPA
     QTVGSRA
//