Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q1IHQ8 (Q1IHQ8_KORVE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Acid345_4592 EMBL ABF43592.1
OrganismKoribacter versatilis (strain Ellin345) [Reference proteome] [HAMAP] EMBL ABF43592.1
Taxonomic identifier204669 [NCBI]
Taxonomic lineageBacteriaAcidobacteriaCandidatus Koribacter

Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain165 – 376212ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding198 – 25356ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3291Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3431Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3431Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3451Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
Q1IHQ8 [UniParc].

Last modified June 13, 2006. Version 1.
Checksum: 326E18F32FDBF85B

FASTA39342,424
        10         20         30         40         50         60 
MAKKIRVGVL FGGRSGEHDV SLLSAASVIN AVDKKKFEVV PIGITKEGKW LTASHAESLL 

        70         80         90        100        110        120 
NGKKAEQQLR AGDPEATPGA AVLAKGEAVL VPPVPQSDRS AIVPFETDAA GHSASSIDVD 

       130        140        150        160        170        180 
VIFPVLHGTF GEDGTIQGLF ELANIPYVGA GVLGSAAGMD KDIMKALFKN AGLPIVKHMT 

       190        200        210        220        230        240 
VLRSQWQREP KKVKKLVESK LKYPVFVKPA NLGSSVGISK AHDSKELGPA LDEAAKFDRK 

       250        260        270        280        290        300 
LVIEQGVGGK KKKAREIECS VLGNDEPKAS VPGEIVPIKE FYDYAAKYLD EGSALEIPAK 

       310        320        330        340        350        360 
LPKSTQKQVQ ELAIRAFQAV DGSGLGRVDF LIDPKSNKLY VNEINTMPGF TSISMYPKLW 

       370        380        390 
EASGLKYTDL ITRLIELALE RHADKQKNQY TKD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000360 Genomic DNA. Translation: ABF43592.1.
RefSeqYP_593666.1. NC_008009.1.

3D structure databases

ProteinModelPortalQ1IHQ8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204669.Acid345_4592.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABF43592; ABF43592; Acid345_4592.
GeneID4071537.
KEGGaba:Acid345_4592.
PATRIC31986587. VBICanKor57425_4905.

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011593.
KOK01921.
OMAMANQKLT.
OrthoDBEOG64BQ73.

Enzyme and pathway databases

BioCycKVER204669:GHL8-4639-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 2 hits.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1IHQ8_KORVE
AccessionPrimary (citable) accession number: Q1IHQ8
Entry history
Integrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)