Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q1IHG6 (EFTU_KORVE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu

Short name=EF-Tu
Gene names
Name:tuf1
Ordered Locus Names:Acid345_1224
AND
Name:tuf2
Ordered Locus Names:Acid345_4684
OrganismKoribacter versatilis (strain Ellin345) [Reference proteome] [HAMAP]
Taxonomic identifier204669 [NCBI]
Taxonomic lineageBacteriaAcidobacteriaCandidatus Koribacter

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 395395Elongation factor Tu HAMAP-Rule MF_00118
PRO_0000337297

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding82 – 865GTP By similarity
Nucleotide binding137 – 1404GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1IHG6 [UniParc].

Last modified June 13, 2006. Version 1.
Checksum: 6A87FB78AC0A789C

FASTA39543,030
        10         20         30         40         50         60 
MAKEKFDRSK PHVNVGTIGH IDHGKTTLTA AITKVLSKHN PKIAFRSFDS IDNAPEERER 

        70         80         90        100        110        120 
GITIATAHVE YETANRHYAH VDCPGHADYI KNMITGAAQM DGAILVVAAT DGPMPQTKEH 

       130        140        150        160        170        180 
VLLARQVGVP YVVVFLNKCD AVEDAELIDL VEMEVRELLN KYGFPGDDLP VVRGSALGAL 

       190        200        210        220        230        240 
NGEAQWEAKI DELMEAVDKN IPLPARDIDK PFLMPIEDIF SISGRGTVVT GRIERGKVKV 

       250        260        270        280        290        300 
GEEVEIVGFR ETRKTVVTGV EMFKKQLDEG LAGDNAGLLL RGIGKDDVER GMVLAKGGSI 

       310        320        330        340        350        360 
TPHTKFKGEV YVLSKEEGGR HTPFFKGYRP QFYFRTTDVT GVATLPAGTE MVMPGDNVAL 

       370        380        390 
EIELITPVAM EKGLRFAIRE GGRTVGAGTI SEIIA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000360 Genomic DNA. Translation: ABF40226.1.
CP000360 Genomic DNA. Translation: ABF43684.1.
RefSeqYP_590300.1. NC_008009.1.
YP_593758.1. NC_008009.1.

3D structure databases

ProteinModelPortalQ1IHG6.
SMRQ1IHG6. Positions 2-394.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204669.Acid345_4684.

Proteomic databases

PRIDEQ1IHG6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABF40226; ABF40226; Acid345_1224.
ABF43684; ABF43684; Acid345_4684.
GeneID4070730.
4072615.
KEGGaba:Acid345_1224.
aba:Acid345_4684.
PATRIC31979326. VBICanKor57425_1308.

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMADYAEIDG.
OrthoDBEOG6R5C6X.

Enzyme and pathway databases

BioCycKVER204669:GHL8-1235-MONOMER.
KVER204669:GHL8-4732-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_KORVE
AccessionPrimary (citable) accession number: Q1IHG6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 13, 2006
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families