Q1IBW2 (Q1IBW2_PSEE4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate dehydrogenase 2 HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222

Gene names

Name:	aroE2 HAMAP MF_00222
Ordered Locus Names:	PSEEN2020

Organism

Pseudomonas entomophila (strain L48) [Complete proteome] [HAMAP]

Taxonomic identifier

384676 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	282 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222
Sequence similarities	Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00222
Ligand	NADP HAMAP MF_00222
Molecular function	Oxidoreductase RuleBase RU004037 HAMAP MF_00222 SAAS SAAS022893 EMBL CAK14853.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	134 – 138	5	NADP By similarity HAMAP MF_00222
Sites
	Active site	74	1	Proton acceptor By similarity HAMAP MF_00222

Sequences

	Sequence		Length	Mass (Da)
	Q1IBW2 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: 1611A6C502E1966D	FASTA	282	29,833
	10 20 30 40 50 60 MNAPGILAGL IGRGIQASRT PALHEAEGDA QALRYLYRLI DADQLGVDDS ALPQLLDAAQ 70 80 90 100 110 120 RTGFTGLNVT FPFKQAILPL LDELSEEARG IGAVNTVVLR DGRRIGHNTD CLGFAEGFRR 130 140 150 160 170 180 GLPDVERRQV VQLGAGGAGS AVAHALLAEG VERLVLFEVD AARGQALVAN LAQRFGAGRA 190 200 210 220 230 240 VLGHDLASAM AEADGLVNTT PVGMAKLPGM PLPAELLRAQ LWVAEIIYFP LETELLRQAR 250 260 270 280 ALGCRTLDGG TMAVFQAVKA FELFSGHPAD AGRMQAHFAR LG

References

[1]

"Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila." Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C., Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F. Nat. Biotechnol. 24:673-679(2006) [PubMed: 16699499] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

[2]

Genoscope Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT573326 Genomic DNA. Translation: CAK14853.1.
RefSeq	YP_607657.1. NC_008027.1.
3D structure databases
ProteinModelPortal	Q1IBW2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1IBW2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4088233.
GenomeReviews	Gene locus PSEEN2020 in contig CT573326_GR.
KEGG	pen:PSEEN2020.
NMPDR	fig|384676.6.peg.1740.
PATRIC	19862212. VBIPseEnt83862_1936.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0169.
HOGENOM	HBG553408.
OMA	HEHEGDA.
PhylomeDB	Q1IBW2.
ProtClustDB	PRK12549.
Enzyme and pathway databases
BioCyc	PENT384676:PSEEN2020-MONOMER.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1IBW2_PSEE4

Accession

Primary (citable) accession number: Q1IBW2

Entry history

Integrated into UniProtKB/TrEMBL:	June 13, 2006
Last sequence update:	June 13, 2006
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)