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Q1I9H0 (UPPP_PSEE4) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:PSEEN2933
OrganismPseudomonas entomophila (strain L48) [Complete proteome] [HAMAP]
Taxonomic identifier384676 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000290752

Regions

Transmembrane43 – 6321Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane109 – 12921Helical; Potential
Transmembrane183 – 20321Helical; Potential
Transmembrane214 – 23421Helical; Potential
Transmembrane248 – 26821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q1I9H0 [UniParc].

Last modified June 13, 2006. Version 1.
Checksum: 2F4DA8239A612C63

FASTA27630,544
        10         20         30         40         50         60 
MDFWSALQAI ILGVVEGLTE FLPISSTGHQ IIVADLINFG GERAMAFNII IQLGAILAVV 

        70         80         90        100        110        120 
WEFRRKIFDV VLGLPTQAPA RRFTANLLIA FFPAVVLGVL FADLIHEYLF NPITVAAALV 

       130        140        150        160        170        180 
VGGVIMLWAE RRQHRIEVDH VDEMSWHHAL KIGFVQCLAM IPGTSRSGST IIGGLLFGLS 

       190        200        210        220        230        240 
RKAATEFSFF LAMPTMVGAA VYSGYKYREL FQPGDLPVFA LGFVVSFIFA MIAVRGLLKF 

       250        260        270 
IANHSYAVFA WYRIAFGLLI LATWEFGWVD WSTAHG 

« Hide

References

[1]"Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila."
Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C., Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F.
Nat. Biotechnol. 24:673-679(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: L48.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT573326 Genomic DNA. Translation: CAK15708.1.
RefSeqYP_608499.1. NC_008027.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING384676.PSEEN2933.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK15708; CAK15708; PSEEN2933.
GeneID4085937.
KEGGpen:PSEEN2933.
PATRIC19863972. VBIPseEnt83862_2810.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycPENT384676:GJB8-2781-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_PSEE4
AccessionPrimary (citable) accession number: Q1I9H0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: June 13, 2006
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families