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Protein

Glutaminase

Gene

glsA

Organism
Pseudomonas entomophila (strain L48)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei61SubstrateUniRule annotation1
Binding sitei111SubstrateUniRule annotation1
Binding sitei155SubstrateUniRule annotation1
Binding sitei162SubstrateUniRule annotation1
Binding sitei186SubstrateUniRule annotation1
Binding sitei238SubstrateUniRule annotation1
Binding sitei256Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:PSEEN3312
OrganismiPseudomonas entomophila (strain L48)
Taxonomic identifieri384676 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000658 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000483421 – 306GlutaminaseAdd BLAST306

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi384676.PSEEN3312.

Structurei

3D structure databases

ProteinModelPortaliQ1I8G2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1I8G2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQALLQEILD HVHPLLAQGQ VAQYIPALAQ VDPNQLGIAV QSLDGQLHCA
60 70 80 90 100
GDAHTPFSIQ SISKVFSLVQ AINHSGEDIW SRLGYEPSGQ AFNSLVQLEV
110 120 130 140 150
EKGRPRNPFI NAGALVICDI NQSRYATPTL SMRDFVRRLS ANPRIVSDAV
160 170 180 190 200
VAESEYEHRA RNAAMAYLMQ AFGNFHNDVD AVLRSYFHHC ALSMSCVDVA
210 220 230 240 250
RGFAFLANGG LCPHSGEQVL SRRQAQQVNA IMATSGLYDE AGNFAYRVGL
260 270 280 290 300
PGKSGVGGGI VAVVPGRYSI CVWSPALNAS GNSLAGLRAL ELLSERMTGS

VFSAIS
Length:306
Mass (Da):32,882
Last modified:June 13, 2006 - v1
Checksum:iD661BD47D42D665E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573326 Genomic DNA. Translation: CAK16066.1.
RefSeqiWP_011534453.1. NC_008027.1.

Genome annotation databases

EnsemblBacteriaiCAK16066; CAK16066; PSEEN3312.
KEGGipen:PSEEN3312.
PATRICi19864730. VBIPseEnt83862_3189.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573326 Genomic DNA. Translation: CAK16066.1.
RefSeqiWP_011534453.1. NC_008027.1.

3D structure databases

ProteinModelPortaliQ1I8G2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi384676.PSEEN3312.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAK16066; CAK16066; PSEEN3312.
KEGGipen:PSEEN3312.
PATRICi19864730. VBIPseEnt83862_3189.

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_PSEE4
AccessioniPrimary (citable) accession number: Q1I8G2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 13, 2006
Last modified: November 2, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.