Q1I6N3 (Q1I6N3_PSEE4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163

Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163

Gene names

Name:	def2 HAMAP MF_00163 EMBL CAK16702.1
Ordered Locus Names:	PSEEN4003

Organism

Pseudomonas entomophila (strain L48) [Complete proteome] [HAMAP]

Taxonomic identifier

384676 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163
Catalytic activity	Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181
Cofactor	Binds 1 Fe2+ ion By similarity. HAMAP MF_00163
Sequence similarities	Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Ontologies

Keywords
Biological process	Protein biosynthesis SAAS SAAS000181 HAMAP MF_00163
Ligand	Iron HAMAP MF_00163 Metal-binding HAMAP MF_00163 SAAS SAAS000181
Molecular function	Hydrolase HAMAP MF_00163 SAAS SAAS000181 EMBL CAK16702.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro peptide deformylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	144	1	By similarity HAMAP MF_00163
	Metal binding	101	1	Iron By similarity HAMAP MF_00163
	Metal binding	143	1	Iron By similarity HAMAP MF_00163
	Metal binding	147	1	Iron By similarity HAMAP MF_00163

Sequences

	Sequence		Length	Mass (Da)
	Q1I6N3 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: C1255D5ED568E0CD	FASTA	178	19,841
	10 20 30 40 50 60 MIRDILKMGD ERLLRIAPPV PEHMLGSAEL RQLIDDMFET MAHVGGVGLA APQIGIDLQL 70 80 90 100 110 120 VIFGFERSER YPDAEAVPRT ILLNPVITPM STEVEDGWEG CLSVPGLRGV VPRYKHISYT 130 140 150 160 170 GVDPDGNPID RFADGFHARV VQHECDHLIG RLYPSRIQDF SKFGYTEVLF PGLDVAED

References

[1]

"Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila." Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C., Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F. Nat. Biotechnol. 24:673-679(2006) [PubMed: 16699499] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

[2]

Genoscope Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT573326 Genomic DNA. Translation: CAK16702.1.
RefSeq	YP_609486.1. NC_008027.1.
3D structure databases
ProteinModelPortal	Q1I6N3.
SMR	Q1I6N3. Positions 2-168.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1I6N3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4086479.
GenomeReviews	Gene locus PSEEN4003 in contig CT573326_GR.
KEGG	pen:PSEEN4003.
NMPDR	fig|384676.6.peg.3439.
PATRIC	19866074. VBIPseEnt83862_3848.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0242.
HOGENOM	HBG665227.
OMA	IRYEGFD.
ProtClustDB	PRK12846.
Enzyme and pathway databases
BioCyc	PENT384676:PSEEN4003-MONOMER.
Family and domain databases
HAMAP	MF_00163. Pep_deformylase. [Tree]
InterPro	IPR000181. Fmet_deformylase. IPR023635. Peptide_deformylase. [Graphical view]
Gene3D	G3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KO	K01462.
PANTHER	PTHR10458. Fmet_deformylase. 1 hit.
Pfam	PF01327. Pep_deformylase. 1 hit. [Graphical view]
PIRSF	PIRSF004749. Pep_def. 1 hit.
PRINTS	PR01576. PDEFORMYLASE.
SUPFAM	SSF56420. Fmet_deformylase. 1 hit.
TIGRFAMs	TIGR00079. Pept_deformyl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1I6N3_PSEE4

Accession

Primary (citable) accession number: Q1I6N3

Entry history

Integrated into UniProtKB/TrEMBL:	June 13, 2006
Last sequence update:	June 13, 2006
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)