Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Pseudomonas entomophila (strain L48)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPENT384676:GJB8-4225-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:PSEEN4447
OrganismiPseudomonas entomophila (strain L48)
Taxonomic identifieri384676 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000658 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 316316Ribosomal RNA large subunit methyltransferase FPRO_0000349928Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi384676.PSEEN4447.

Structurei

3D structure databases

ProteinModelPortaliQ1I5F5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiPOG091H05H4.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F. 1 hit.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1I5F5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDKPTLHPR NRHQGRYDFP ALIKAHPDLA RFTITNPYGK PSIDFANPEA
60 70 80 90 100
VRVFNRALLK AQYGVQHWDI PADYLCPPIP GRADYIHVLA DLLAEDNAGD
110 120 130 140 150
VPRGAQVRAL DIGVGANCIY PLLGHSDYRW RFLGSDIDTT ALASAKAIVQ
160 170 180 190 200
ANKLDKAIGL RQQTQPKHIL AGLLQADERF DVTLCNPPFH ASREEATRGS
210 220 230 240 250
QRKWKNLGKQ DPKRKLPVLN FGGQNNELWC EGGEIRFVSQ LVGESVQYAE
260 270 280 290 300
QVLWFTSLVS KASNLPGIEA ALKKAGVKAL RIVEMGQGQK QSRMVAWSFH
310
DDAARQAWHA RRKSQA
Length:316
Mass (Da):35,242
Last modified:June 13, 2006 - v1
Checksum:i38F20C8459EDAA2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573326 Genomic DNA. Translation: CAK17130.1.
RefSeqiWP_011535501.1. NC_008027.1.

Genome annotation databases

EnsemblBacteriaiCAK17130; CAK17130; PSEEN4447.
KEGGipen:PSEEN4447.
PATRICi19866958. VBIPseEnt83862_4284.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573326 Genomic DNA. Translation: CAK17130.1.
RefSeqiWP_011535501.1. NC_008027.1.

3D structure databases

ProteinModelPortaliQ1I5F5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi384676.PSEEN4447.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAK17130; CAK17130; PSEEN4447.
KEGGipen:PSEEN4447.
PATRICi19866958. VBIPseEnt83862_4284.

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiPOG091H05H4.

Enzyme and pathway databases

BioCyciPENT384676:GJB8-4225-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F. 1 hit.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRLMF_PSEE4
AccessioniPrimary (citable) accession number: Q1I5F5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: June 13, 2006
Last modified: September 7, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.