Q1I563 (ALGL_PSEE4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Alginate lyase
EC=4.2.2.3

Alternative name(s):
Poly(beta-D-mannuronate) lyase
Poly(mana) alginate lyase

Gene names

Name:	algL
Ordered Locus Names:	PSEEN4542

Organism

Pseudomonas entomophila (strain L48) [Complete proteome] [HAMAP]

Taxonomic identifier

384676 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	367 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond By similarity. HAMAP MF_00557
Catalytic activity	Eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. HAMAP MF_00557
Subcellular location	Periplasm Potential HAMAP MF_00557.
Sequence similarities	Belongs to the polysaccharide lyase 5 family.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	alginic acid catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	poly(beta-D-mannuronate) lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential
	Chain	25 – 367	343	Alginate lyase HAMAP MF_00557		PRO_1000061111

Sequences

	Sequence		Length	Mass (Da)
	Q1I563 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: B564B2BBC028CF80	FASTA	367	40,986
	10 20 30 40 50 60 MTIINRKTAP ALLALALFGG AAQAALVPPQ GYYEGIEKLK SSDGDFRCEA APRPYTGSLR 70 80 90 100 110 120 FRSKYEGSDK ARATLNVASE KAFRASTKDI TTLEKGVSKM VGQYMRDGRP AQLDCALTWL 130 140 150 160 170 180 GTWARADALM SSDYNHTGKS MRKWALGSMS GSWLRLKFSN SQPLAAHQAE AEQIEKWFAR 190 200 210 220 230 240 LAQQTVRDWS GLPLEKINNH SYWAAWSVMA TAVATDRRDL FDWAVKEYKV GANQVDEQGF 250 260 270 280 290 300 LPNELKRRQR ALAYHNYALP PLAMIASFAQ ANGVDLRKEN NFALQRLGEG VLAGARDPSQ 310 320 330 340 350 360 FTAHAGVKQD LHDLKIDSKY AWLEPWCALY HCVGDTLERK HDMQPFDSFR LGGDVTRVYD PGAESKK

References

[1]

"Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila." Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C., Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F. Nat. Biotechnol. 24:673-679(2006) [PubMed: 16699499] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: L48.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT573326 Genomic DNA. Translation: CAK17222.1.
RefSeq	YP_610006.1. NC_008027.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1I563.
Protein family/group databases
CAZy	PL5. Polysaccharide Lyase Family 5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4089652.
GenomeReviews	Gene locus PSEEN4542 in contig CT573326_GR.
KEGG	pen:PSEEN4542.
NMPDR	fig|384676.6.peg.3938.
PATRIC	19867148. VBIPseEnt83862_4379.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG42597.
HOGENOM	HBG336064.
OMA	AAWSVMA.
ProtClustDB	PRK00325.
Enzyme and pathway databases
BioCyc	PENT384676:PSEEN4542-MONOMER.
Family and domain databases
HAMAP	MF_00557. Alginate_lyase. [Tree]
InterPro	IPR022859. Alginate_lyase. IPR008397. Alginate_lyase_dom. IPR008929. Chondroitin_lyas. [Graphical view]
Gene3D	G3DSA:1.50.10.110. Alginate_lyase. 1 hit.
KO	K01729.
Pfam	PF05426. Alginate_lyase. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALGL_PSEE4

Accession

Primary (citable) accession number: Q1I563

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	June 13, 2006
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program