Reviewed, UniProtKB/Swiss-Prot Q1I4M5 (UBIC1_PSEE4)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase 1
      Short name=CL 1
      Short name=CPL 1
    EC=4.1.3.40

Gene names

Name:	ubiC1
Ordered Locus Names:	PSEEN4753

Organism

Pseudomonas entomophila (strain L48) [Complete proteome] [HAMAP]

Taxonomic identifier

384676 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity HAMAP MF_01632.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 185	185	Probable chorismate--pyruvate lyase 1 HAMAP MF_01632		PRO_0000292072
Sites
	Binding site	68	1	Substrate By similarity
	Binding site	106	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1I4M5-1 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: 5FCE14D9C890C66E	FASTA	185	20,648
	10 20 30 40 50 60 MDNLWTSLPL PGLSDDQRHW LFAPGSLTLR LKALGRFSLE VTQQRIDFPE PGEAHALGCT 70 80 90 100 110 120 TDSPAWIREV ALKIDDQVMV CARSLTPMRE RRPAWPELAG YGGEPLGSML YNTPDIHRGA 130 140 150 160 170 180 FECQRPQADD PLSRLATSLG QPSGKLLARR SRFLRDGQPL LIAECFVEGF WALLQERSAP LKLAI

References

[1]

"Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila." Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C., Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F. Nat. Biotechnol. 24:673-679(2006) [PubMed: 16699499] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT573326 Genomic DNA. Translation: CAK17411.1.
RefSeq	YP_610194.1.
3D structure databases
SMR	Q1I4M5. Positions 9-171.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1I4M5.
Genome annotation databases
GeneID	4086197.
GenomeReviews	Gene locus PSEEN4753 in contig CT573326_GR.
KEGG	pen:PSEEN4753.
NMPDR	fig|384676.6.peg.4094.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3161.
HOGENOM	HBG644467.
OMA	GTPYVAA.
Enzyme and pathway databases
BioCyc	PENT384676:PSEEN4753-MONOMER.
Family and domain databases
HAMAP	MF_01632. UbiC. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC1_PSEE4

Accession

Primary (citable) accession number: Q1I4M5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	June 13, 2006
Last modified:	January 19, 2010
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)