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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Pseudomonas entomophila (strain L48)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI)
  4. Enolase (eno)
  5. Pyruvate kinase (pykA), Pyruvate kinase (pykF)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei36SubstrateUniRule annotation1
Binding sitei113SubstrateUniRule annotation1
Binding sitei146SubstrateUniRule annotation1
Binding sitei197ATPUniRule annotation1
Binding sitei314ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi340 – 343ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:PSEEN5022
OrganismiPseudomonas entomophila (strain L48)
Taxonomic identifieri384676 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000658 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000580371 – 387Phosphoglycerate kinaseAdd BLAST387

Proteomic databases

PRIDEiQ1I3Y0.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi384676.PSEEN5022.

Structurei

3D structure databases

ProteinModelPortaliQ1I3Y0.
SMRiQ1I3Y0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 23Substrate bindingUniRule annotation3
Regioni59 – 62Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA. Bacteria.
COG0126. LUCA.
HOGENOMiHOG000227107.
KOiK00927.
OMAiDMIFDIG.
OrthoDBiPOG091H00YN.

Family and domain databases

Gene3Di3.40.50.1260. 2 hits.
HAMAPiMF_00145. Phosphoglyc_kinase. 1 hit.
InterProiView protein in InterPro
IPR001576. Phosphoglycerate_kinase.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiView protein in Pfam
PF00162. PGK. 1 hit.
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiView protein in PROSITE
PS00111. PGLYCERATE_KINASE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1I3Y0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVLKMTDLD LQGKRVLIRE DLNVPVKDGV VTSDARILAA LPTIKLALEK
60 70 80 90 100
GAAVMVCSHL GRPTEGEFSE ENSLKPVAAY LSKALGREVP LVADYLDGVE
110 120 130 140 150
VKAGDLVLFE NVRFNKGEKK NADELAQKYA ALCDVFVMDA FGTAHRAEGS
160 170 180 190 200
THGVAKFAKV ATAGPLLAAE LDALGKALKA PAKPMAAIVA GSKVSTKLDV
210 220 230 240 250
LNSLSTVCDQ LIVGGGIANT FLAAAGHPVG KSLYEPDLVE TAKAIAAKVS
260 270 280 290 300
VPLPVDVVVA KAFAEDAEAT VKAIADVAAD DMILDIGPKT AEQFAELLKT
310 320 330 340 350
SKTILWNGPV GVFEFDQFGN GTKVLAKAIA DSAAFSIAGG GDTLAAIDKY
360 370 380
GVGADISYIS TGGGAFLEFV EGKVLPAVAI LEERAKA
Length:387
Mass (Da):40,120
Last modified:June 13, 2006 - v1
Checksum:iE4B722440E3EA513
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573326 Genomic DNA. Translation: CAK17656.1.
RefSeqiWP_011536016.1. NC_008027.1.

Genome annotation databases

EnsemblBacteriaiCAK17656; CAK17656; PSEEN5022.
GeneIDi32807961.
KEGGipen:PSEEN5022.

Similar proteinsi

Entry informationi

Entry nameiPGK_PSEE4
AccessioniPrimary (citable) accession number: Q1I3Y0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 13, 2006
Last modified: August 30, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families