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Q1I3J6 (Q1I3J6_PSEE4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase 3 HAMAP MF_00051
Short name=SHMT 3 HAMAP MF_00051
Short name=Serine methylase 3 HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA-2 EMBL CAK17790.1
Synonyms:glyA3 HAMAP MF_00051
Ordered Locus Names:PSEEN5162
OrganismPseudomonas entomophila (strain L48) [Complete proteome] [HAMAP]
Taxonomic identifier384676 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. RuleBase RU000585 HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. RuleBase RU000585 HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000585 HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU000585

Subunit structure

Homotetramer By similarity. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. RuleBase RU004104 HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2301N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
Q1I3J6 [UniParc].

Last modified June 13, 2006. Version 1.
Checksum: C27786E6116C7366

FASTA41744,630
        10         20         30         40         50         60 
MFSKQDQIQG YDDALLAAMN AEEQRQEDHI ELIASENYTS KRVMQAQGSG LTNKYAEGYP 

        70         80         90        100        110        120 
GKRYYGGCEH VDKVEALAIE RAKQLFGADY ANVQPHSGSS ANSAVYLALL QAGDTILGMS 

       130        140        150        160        170        180 
LAHGGHLTHG AKVSSSGKLY NAVQYGIDTT TGLIDYDEVE RLAVEHKPKM IVAGFSAYSK 

       190        200        210        220        230        240 
TLDFPRFRQI ADKVGALLFV DMAHVAGLVA AGLYPNPIPF ADVVTTTTHK TLRGPRGGLI 

       250        260        270        280        290        300 
LAKSNEEIEK KLNAAVFPGA QGGPLMHVIA AKAVCFKEAL EPGFKAYQKQ VIENAQAMAQ 

       310        320        330        340        350        360 
VFIERGYDVV SGGTDNHLFL VSLIRQGLTG KDADAALGRA HITVNKNAVP NDPQSPFVTS 

       370        380        390        400        410 
GLRIGTPAVT TRGFKVAQCV ALAGWICDVL DNLGDADVEA DVAKNVAALC ADFPVYR

« Hide

References

[1]"Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila."
Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C., Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F.
Nat. Biotechnol. 24:673-679(2006) [PubMed: 16699499] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]Genoscope
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CT573326 Genomic DNA. Translation: CAK17790.1.
RefSeqYP_610573.1. NC_008027.1.

3D structure databases

ProteinModelPortalQ1I3J6.
SMRQ1I3J6. Positions 1-416.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1I3J6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4087393.
GenomeReviewsGene locus PSEEN5162 in contig CT573326_GR.
KEGGpen:PSEEN5162.
NMPDRfig|384676.6.peg.4467.
PATRIC19868324. VBIPseEnt83862_4957.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0112.
HOGENOMHBG301263.
OMAADVEANV.
PhylomeDBQ1I3J6.
ProtClustDBPRK13034.

Enzyme and pathway databases

BioCycPENT384676:PSEEN5162-MONOMER.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
IPR019798. Ser_HO-MeTrfase_PLP_BS.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00600.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00096. SHMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1I3J6_PSEE4
AccessionPrimary (citable) accession number: Q1I3J6
Entry history
Integrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info