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Protein

Ribonuclease PH

Gene

rph

Organism
Pseudomonas entomophila (strain L48)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates.UniRule annotationSAAS annotation

Catalytic activityi

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotationSAAS annotationImported, Transferase
Biological processtRNA processingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease PHUniRule annotationSAAS annotation (EC:2.7.7.56UniRule annotationSAAS annotation)
Short name:
RNase PHUniRule annotation
Alternative name(s):
tRNA nucleotidyltransferaseUniRule annotation
Gene namesi
Name:rphUniRule annotationImported
Ordered Locus Names:PSEEN5439Imported
OrganismiPseudomonas entomophila (strain L48)Imported
Taxonomic identifieri384676 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000658 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi384676.PSEEN5439.

Structurei

3D structure databases

ProteinModelPortaliQ1I2T6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 154RNase_PHInterPro annotationAdd BLAST131
Domaini172 – 239RNase_PH_CInterPro annotationAdd BLAST68

Sequence similaritiesi

Belongs to the RNase PH family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105ED0. Bacteria.
COG0689. LUCA.
HOGENOMiHOG000229516.
KOiK00989.
OMAiKGKGQGW.
OrthoDBiPOG091H03ML.

Family and domain databases

CDDicd11362. RNase_PH_bact. 1 hit.
Gene3Di3.30.230.70. 1 hit.
HAMAPiMF_00564. RNase_PH. 1 hit.
InterProiView protein in InterPro
IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR036345. ExoRNase_PH_dom2_sf.
IPR027408. PNPase/RNase_PH_dom_sf.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
PfamiView protein in Pfam
PF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsiTIGR01966. RNasePH. 1 hit.
PROSITEiView protein in PROSITE
PS01277. RIBONUCLEASE_PH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1I2T6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGRFKVPVQ VSQMKRPSGR AADQLRSIRI TRNYTKHAEG SVLVEFGDTK
60 70 80 90 100
VICTVSVENG VPRFLKGQGQ GWLTAEYGML PRSTGERNQR EASRGKQGGR
110 120 130 140 150
TLEIQRLIGR SLRAALDMSK LGDITLYVDC DVIQADGGTR TASITGAMVA
160 170 180 190 200
LCDALAVIKK RGGLKGGNPL KHMIAAVSVG MYQGEAVLDL DYLEDSAAET
210 220 230 240 250
DLNVVMTSAG GFIEVQGTAE GAPFQPEDFN AMLALAQKGM GEIFELQQAA

LAD
Length:253
Mass (Da):27,109
Last modified:June 13, 2006 - v1
Checksum:iA7797FC0E393D1D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573326 Genomic DNA. Translation: CAK18050.1.

Genome annotation databases

EnsemblBacteriaiCAK18050; CAK18050; PSEEN5439.
KEGGipen:PSEEN5439.

Similar proteinsi

Entry informationi

Entry nameiQ1I2T6_PSEE4
AccessioniPrimary (citable) accession number: Q1I2T6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: November 22, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported