Reviewed, UniProtKB/Swiss-Prot Q1I2R4 (UBIC2_PSEE4)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase 2
      Short name=CL 2
      Short name=CPL 2
    EC=4.1.3.40

Gene names

Name:	ubiC2
Ordered Locus Names:	PSEEN5461

Organism

Pseudomonas entomophila (strain L48) [Complete proteome] [HAMAP]

Taxonomic identifier

384676 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity.
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 185	185	Probable chorismate--pyruvate lyase 2 HAMAP MF_01632		PRO_0000292073
Sites
	Binding site	80	1	Substrate By similarity
	Binding site	118	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1I2R4-1 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: 538A795DA07D352A	FASTA	185	21,060
	10 20 30 40 50 60 MPYETPQAAA VAWLPYSQLA TTLDQPTLDW LFDEGSLTRR LTRLSHDHFS VTPLFEGWQP 70 80 90 100 110 120 LRDDECAALG LAPGEEGWVR EVYLRGHDQP WVFARSVAGR SVLERGGLDL ETLGTRSLGE 130 140 150 160 170 180 LLFCDQAFIR HPLEACRYPQ TWLPTKVAHE GLWGRRSRFE RSGLDLLVAE VFLPALWQAA KEETR

References

[1]

"Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila." Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C., Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F. Nat. Biotechnol. 24:673-679(2006) [PubMed: 16699499] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CT573326 Genomic DNA. Translation: CAK18072.1.
RefSeq	YP_610855.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1I2R4.
Genome annotation databases
GeneID	4087232.
GenomeReviews	Gene locus PSEEN5461 in contig CT573326_GR.
KEGG	pen:PSEEN5461.
NMPDR	fig|384676.6.peg.4732.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1I2R4.
OMA	WGRRSRF.
Enzyme and pathway databases
BioCyc	PENT384676:PSEEN5461-MON.
Family and domain databases
HAMAP	MF_01632. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC2_PSEE4

Accession

Primary (citable) accession number: Q1I2R4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	June 13, 2006
Last modified:	November 3, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)