Reviewed, UniProtKB/Swiss-Prot Q1I2G6 (HEM6_PSEE4)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3

Gene names

Name:	hemF
Ordered Locus Names:	PSEEN0030

Organism

Pseudomonas entomophila (strain L48) [Complete proteome] [HAMAP]

Taxonomic identifier

384676 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Coproporphyrinogen III oxidase, aerobic		PRO_1000019485

Sequences

	Sequence		Length	Mass (Da)
	Q1I2G6-1 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: CAB87F75FBFD2652	FASTA	303	34,444
	10 20 30 40 50 60 MTSRTEAVKA YLLDLQDRIC SALETEDGGA RFVEDAWVRD AGGGGRTRVI GEGKVIEKGG 70 80 90 100 110 120 VNFSHVFGAG LPPSASAHRP ELAGRGFEAL GVSLVIHPHN PHVPTSHANV RFFIAEKEGE 130 140 150 160 170 180 EAVWWFGGGF DLTPYYGNEE DCVHWHRVAE QACAPFGADV YPRYKAWCDR YFHLKHRGEP 190 200 210 220 230 240 RGIGGLFFDD LNEWDFDTCF AFMRAIGDAY VDAYLPIIQR RKDTPYTAKQ REFQEYRRGR 250 260 270 280 290 300 YVEFNLVYDR GTLFGLQSGG RTESILMSLP PQVRWGYDWK AEPGSEEARL TDYFLQDRDW LAQ

References

[1]

"Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila." Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C., Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F. Nat. Biotechnol. 24:673-679(2006) [PubMed: 16699499] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CT573326 Genomic DNA. Translation: CAK13024.1.
RefSeq	YP_605841.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4085729.
GenomeReviews	Gene locus PSEEN0030 in contig CT573326_GR.
KEGG	pen:PSEEN0030.
NMPDR	fig|384676.6.peg.25.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1I2G6.
Enzyme and pathway databases
BioCyc	PENT384676:PSEEN0030-MON.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_PSEE4

Accession

Primary (citable) accession number: Q1I2G6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 13, 2006
Last modified:	November 4, 2008
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)