Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nucleoprotein

Gene

NP

Organism
Influenza A virus (A/WSN/1933 TS61(H1N1))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Host-virus interactionSAAS annotation, Viral penetration into host nucleusSAAS annotation, Virus entry into host cell

Keywords - Ligandi

RNA-bindingSAAS annotation, Viral nucleoproteinUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
NucleoproteinUniRule annotationSAAS annotation
Gene namesi
Name:NPUniRule annotationImported
OrganismiInfluenza A virus (A/WSN/1933 TS61(H1N1))Imported
Taxonomic identifieri370129 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A

Subcellular locationi

  • Host nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid proteinSAAS annotation, Host nucleusUniRule annotationSAAS annotation, Virion

Interactioni

Protein-protein interaction databases

DIPiDIP-60419N.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IQHX-ray3.20A/B/C8-498[»]
2YMNelectron microscopy20.00A/B/C/D/E/F1-498[»]
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ1I2B5.

Family & Domainsi

Sequence similaritiesi

Belongs to the influenza viruses nucleoprotein family.UniRule annotationSAAS annotation

Family and domain databases

InterProiIPR002141. Flu_NP.
[Graphical view]
PfamiPF00506. Flu_NP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1I2B5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATKGTKRSY EQMETDGERQ NATEIRASVG KMIDGIGRFY IQMCTELKLS
60 70 80 90 100
DYEGRLIQNS LTIERMVLSA FDERRNKYLE EHPSAGKDPK KTGGPIYRRV
110 120 130 140 150
DGKWRRELIL YDKEEIRRIW RQANNGDDAT AGLTHMMIWH SNLNDATYQR
160 170 180 190 200
TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGVGTMV MELIRMIKRG
210 220 230 240 250
INDRNFWRGE NGRRTRIAYE RMCNILKGKF QTAAQRTMVD QVRESRNPGN
260 270 280 290 300
AEFEDLIFLA RSALILRGSV AHKSCLPACV YGSAVASGYD FEREGYSLVG
310 320 330 340 350
IDPFRLLQNS QVYSLIRPNE NPAHKSQLVW MACHSAAFED LRVSSFIRGT
360 370 380 390 400
KVVPRGKLST RGVQIASNEN METMESSTLE LRSRYWAIRT RSGGNTNQQR
410 420 430 440 450
ASSGQISIQP TFSVQRNLPF DRPTIMAAFT GNTEGRTSDM RTEIIRLMES
460 470 480 490
ARPEDVSFQG RGVFELSDEK ATSPIVPSFD MSNEGSYFFG DNAEEYDN
Length:498
Mass (Da):56,377
Last modified:June 13, 2006 - v1
Checksum:i91390B2963EAB5A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CY010791 Genomic RNA. Translation: ABF47959.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CY010791 Genomic RNA. Translation: ABF47959.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IQHX-ray3.20A/B/C8-498[»]
2YMNelectron microscopy20.00A/B/C/D/E/F1-498[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60419N.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ1I2B5.

Family and domain databases

InterProiIPR002141. Flu_NP.
[Graphical view]
PfamiPF00506. Flu_NP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA."
    Ye Q., Krug R.M., Tao Y.J.
    Nature 444:1078-1082(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.20 ANGSTROMS) OF 8-498.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A/WSN/1933 TS61Imported.
  3. The NIAID Influenza Genome Sequencing Consortium
    Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A/WSN/1933 TS61Imported.
  4. "Organization of the influenza virus replication machinery."
    Moeller A., Kirchdoerfer R.N., Potter C.S., Carragher B., Wilson I.A.
    Science 338:1631-1634(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY ELECTRON MICROSCOPY (20.00 ANGSTROMS).

Entry informationi

Entry nameiQ1I2B5_9INFA
AccessioniPrimary (citable) accession number: Q1I2B5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: May 11, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.