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Protein

Dystrobrevin

Gene

DTNB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DystrobrevinUniRule annotation
Gene namesi
Name:DTNBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ1I0L3.
PeptideAtlasiQ1I0L3.
PRIDEiQ1I0L3.

PTM databases

iPTMnetiQ1I0L3.

Expressioni

Gene expression databases

GenevisibleiQ1I0L3. HS.

Structurei

3D structure databases

ProteinModelPortaliQ1I0L3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini237 – 284ZZ-typeInterPro annotationAdd BLAST48

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili429 – 460Sequence analysisAdd BLAST32
Coiled coili475 – 519Sequence analysisAdd BLAST45

Sequence similaritiesi

Belongs to the dystrophin family. Dystrobrevin subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4301. Eukaryota.
ENOG410XP3C. LUCA.
HOVERGENiHBG005539.

Family and domain databases

InterProiView protein in InterPro
IPR017432. Distrobrevin.
IPR011992. EF-hand-dom_pair.
IPR015153. EF-hand_dom_typ1.
IPR015154. EF-hand_dom_typ2.
IPR000433. Znf_ZZ.
PfamiView protein in Pfam
PF09068. EF-hand_2. 1 hit.
PF09069. EF-hand_3. 1 hit.
PF00569. ZZ. 1 hit.
PIRSFiPIRSF038204. Distrobrevin. 1 hit.
SMARTiView protein in SMART
SM00291. ZnF_ZZ. 1 hit.
SUPFAMiSSF47473. SSF47473. 2 hits.
PROSITEiView protein in PROSITE
PS01357. ZF_ZZ_1. 1 hit.
PS50135. ZF_ZZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1I0L3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEESGNKRK TMAEKRQLFI EMRAQNFDVI RLSTYRTACK LRFVQKRCNL
60 70 80 90 100
HLVDIWNMIE AFRDNGLNTL DHTTEISVSR LETVISSIYY QLNKRLPSTH
110 120 130 140 150
QISVEQSISL LLNFMIAAYD SEGRGKLTVF SVKAMLATMC GGKMLDKLRY
160 170 180 190 200
VFSQMSDSNG LMIFSKFDQF LKEVLKLPTA VFEGPSFGYT EHSVRTCFPQ
210 220 230 240 250
QRKIMLNMFL DTMMADPPPQ CLVWLPLMHR LAHVENVFHP VECSYCRCES
260 270 280 290 300
MMGFRYRCQQ CHNYQLCQNC FWRGHAGGPH SNQHQMKEHS SWKSPAKKLS
310 320 330 340 350
HAISKSLGCV PTREPPHPVF PEQPEKPLDL AHIVPPRPLT NMNDTMVSHM
360 370 380 390 400
SSGVPTPTKR LQYSQDIPSH LADEHALIAS YVARLQHCAR VLDSPSRLDE
410 420 430 440 450
EHRLIARYAA RLAAEAGNVT RPPTDLSFNF DANKQQRQLI AELENKNREI
460 470 480 490 500
LQEIQRLRLE HEQASQPTPE KAQQNPTLLA ELRLLRQRKD ELEQRMSALQ
510 520 530 540 550
ESRRELMVQL EELMKLLKAQ ATGSPHTSPT HGGGRPMPMP VRSTSAGSTP
560 570 580 590 600
THCPQDSLSG VGGDVQEAFA QGTRRNLRND LLVAADSITN TMSSLVKELH

SG
Length:602
Mass (Da):68,452
Last modified:June 13, 2006 - v1
Checksum:i863DD6D4C17EF7BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ160290 mRNA. Translation: ABA08463.1.
RefSeqiNP_001243233.1. NM_001256304.1.
XP_005264239.1. XM_005264182.1.
UniGeneiHs.307720.

Genome annotation databases

GeneIDi1838.

Similar proteinsi

Entry informationi

Entry nameiQ1I0L3_HUMAN
AccessioniPrimary (citable) accession number: Q1I0L3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: August 30, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.