Q1HR83 (Q1HR83_AEDAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptidyl-prolyl cis-trans isomerase RuleBase RU004231

Gene names

ORF Names:

AAEL007883

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti) [Reference proteome] EMBL ABF18244.1

Taxonomic identifier

7159 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia

Protein attributes

Sequence length	108 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 PPIase FKBP-type domain. RuleBase RU004231

Ontologies

Keywords
Molecular function	Isomerase Rotamase RuleBase RU003715
Technical term	3D-structure PDB 3UQI PDB 2LPV Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: UniProtKB-KW protein peptidyl-prolyl isomerization Inferred from electronic annotation. Source: GOC
Molecular_function	peptidyl-prolyl cis-trans isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1HR83 [UniParc]. Last modified June 13, 2006. Version 1. Checksum: 75101FF9E06D3ADA	FASTA	108	11,539
	10 20 30 40 50 60 MGVQVVTLAA GDEATYPKAG QVAVVHYTGT LADGKVFDSS RTRGKPFRFT VGRGEVIRGW 70 80 90 100 DEGVAQMSVG QRAKLVCSPD YAYGSRGHPG VIPPNATLTF DVELLRVE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P., Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H., Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G. , Utterback T., Rogers Y.-H., Kravitz S., Fraser C.M. Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Liverpool EMBL EAT40395.1.
[2]	Ribeiro J.M.C., Chandra P.K., Calvo E., Pham V.M., Wikel S.K. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti." Ribeiro J.M.C., Arca B., Lombardo F., Calvo E., Phan V.M., Chandra P.K., Wikel S.K. BMC Genomics 8:6-6(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[4]	"Genome sequence of Aedes aegypti, a major arbovirus vector." Nene V., Wortman J.R., Lawson D., Haas B., Kodira C., Tu Z.J., Loftus B., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P. , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., Debruyn B., Decaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston J.S., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'leary S., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.H., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M., Vanzee J.P., Verjovski-Almeida S., Werner D., White O., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Birren B., Fraser-Liggett C.M., Severson D.W. Science 316:1718-1723(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Liverpool EMBL EAT40395.1 and LVPib12.
[5]	"High-resolution crystal structure of FKBP12 from Aedes aegypti." Rajan S., Saw K.Q., Nguyen Q.T., Baek K., Yoon H.S. Protein Sci. 21:1080-1084(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.30 ANGSTROMS).
[6]	"Solution structure of FK506-binding protein 12 from Aedes aegypti." Chakraborty G., Shin J., Nguyen Q.T., Harikishore A., Baek K., Yoon H.S. Proteins 80:2476-2481(2012) [PubMed] [Europe PMC] [Abstract] Cited for: STRUCTURE BY NMR.
[7]	VectorBase Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Liverpool EMBL EAT40395.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

DQ440211 mRNA. Translation: ABF18244.1.
CH477472 Genomic DNA. Translation: EAT40395.1.
CH477472 Genomic DNA. Translation: EJY57709.1.
CH477472 Genomic DNA. Translation: EJY57710.1.

RefSeq

XP_001652968.1. XM_001652918.1.
XP_001652969.1. XM_001652919.1.
XP_001652970.1. XM_001652920.1.

UniGene

Aae.20550.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2LPV	NMR	-	A	1-108	[»]
3UQI	X-ray	1.30	A	1-108	[»]

SMR

Q1HR83. Positions 2-108.

ModBase

Search...

Protein-protein interaction databases

STRING

7159.AAEL007883-PA.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblMetazoa

AAEL007883-RA; AAEL007883-PA; AAEL007883.
AAEL007883-RB; "AAEL007883-PB "; AAEL007883.
AAEL007883-RC; "AAEL007883-PC "; AAEL007883.

GeneID

5569745.

KEGG

aag:AaeL_AAEL007883.

VectorBase

AAEL007883. Aedes aegypti.

Phylogenomic databases

eggNOG

COG0545.

HOGENOM

HOG000154887.

InParanoid

Q1HR83.

KO

K09568.

OMA

FKIGHQE.

OrthoDB

EOG4SQVD7.

Family and domain databases

InterPro

IPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view]

PANTHER

PTHR10516. PTHR10516. 1 hit.

Pfam

PF00254. FKBP_C. 1 hit.
[Graphical view]

PROSITE

PS50059. FKBP_PPIASE. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q1HR83_AEDAE

Accession

Primary (citable) accession number: Q1HR83

Entry history

Integrated into UniProtKB/TrEMBL:	June 13, 2006
Last sequence update:	June 13, 2006
Last modified:	May 1, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)