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Q1HQ66

- Q1HQ66_BOMMO

UniProt

Q1HQ66 - Q1HQ66_BOMMO

Protein
Submitted name:

Phosphoribosylaminoimidazole carboxylase

Gene

LOC732910

Organism
Bombyx mori (Silk moth)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (13 Jun 2006)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei20 – 201Sulfate 2; via amide nitrogen and carbonyl oxygenImported
    Binding sitei93 – 931Sulfate 4Imported
    Binding sitei93 – 931Sulfate 5Imported
    Binding sitei104 – 1041Sulfate 6Imported
    Binding sitei110 – 1101Sulfate 6Imported
    Binding sitei145 – 1451Sulfate 7; via amide nitrogenImported
    Binding sitei167 – 1671Sulfate 8Imported
    Binding sitei205 – 2051Sulfate 8; via amide nitrogenImported
    Binding sitei217 – 2171Sulfate 6Imported
    Binding sitei332 – 3321Sulfate 10Imported
    Binding sitei332 – 3321Sulfate 11Imported
    Binding sitei332 – 3321Sulfate 9Imported
    Binding sitei357 – 3571Sulfate 11Imported

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Source: InterPro

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Phosphoribosylaminoimidazole carboxylaseImported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:LOC732910Imported
    OrganismiBombyx mori (Silk moth)
    Taxonomic identifieri7091 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaLepidopteraGlossataDitrysiaBombycoideaBombycidaeBombycinaeBombyx
    ProteomesiUP000005204: Unassembled WGS sequence

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4JA0X-ray2.80A/B/C/D1-425[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni20 – 212Sulfate 1 bindingImported

    Phylogenomic databases

    KOiK01587.
    OMAiTAFTRKC.
    OrthoDBiEOG725DHT.

    Family and domain databases

    Gene3Di3.30.470.20. 1 hit.
    3.40.50.7700. 1 hit.
    InterProiIPR013816. ATP_grasp_subdomain_2.
    IPR000031. PurE_dom.
    IPR028923. SAICAR_synt/ADE2_N.
    IPR018236. SAICAR_synthetase_CS.
    [Graphical view]
    PfamiPF00731. AIRC. 1 hit.
    PF01259. SAICAR_synt. 1 hit.
    [Graphical view]
    SMARTiSM01001. AIRC. 1 hit.
    [Graphical view]
    SUPFAMiSSF52255. SSF52255. 1 hit.
    PROSITEiPS01057. SAICAR_SYNTHETASE_1. 1 hit.
    PS01058. SAICAR_SYNTHETASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1HQ66-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSHPKQVGQY KLGKLLIEGK TKQVFDVPDQ PGYCLLLNKD RITAGDGVKA    50
    HDLEGKAAIS NQTNAKVFEI LKSAGIKTAF VKIASETAFL SKKCEMIPIE 100
    WVTRRLATGS FLKRNPGVPE GFRFTPPKQE TFFKDDANHD PQWSEEQIIS 150
    AKFNYNGLLI GRDEVDYMRK ATILIFEILE KAWALRDCAL IDMKIEFGVD 200
    TEGSIVLADV IDSDSWRLWP SGDKRLMVDK QVYRNLTTVT AADLDTVKRN 250
    FAWVKDQLDF LKPTIHHKVV VFMGSPADQE HCQKIAKAAR ELGLDVDLRV 300
    TSAHKATEET LRIMQQYEDT HGALVFIAVA GRSNGLGPVL SGNTSYPVIN 350
    CPPPSDKLVQ DIWSSLSVPS GLGCATVIYP DSAALMAAQI IGLQDYLVWG 400
    RLRSKQLDMA HSLRQADKKL RNQTA 425
    Length:425
    Mass (Da):47,344
    Last modified:June 13, 2006 - v1
    Checksum:i245092F377D7EA1F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EF105371 Genomic DNA. No translation available.
    DQ443186 mRNA. Translation: ABF51275.1.
    RefSeqiNP_001040376.1. NM_001046911.1.
    UniGeneiBmo.285.

    Genome annotation databases

    EnsemblMetazoaiBGIBMGA007935-RA; BGIBMGA007935-TA; BGIBMGA007935.
    GeneIDi732910.
    KEGGibmor:732910.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EF105371 Genomic DNA. No translation available.
    DQ443186 mRNA. Translation: ABF51275.1 .
    RefSeqi NP_001040376.1. NM_001046911.1.
    UniGenei Bmo.285.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4JA0 X-ray 2.80 A/B/C/D 1-425 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai BGIBMGA007935-RA ; BGIBMGA007935-TA ; BGIBMGA007935 .
    GeneIDi 732910.
    KEGGi bmor:732910.

    Phylogenomic databases

    KOi K01587.
    OMAi TAFTRKC.
    OrthoDBi EOG725DHT.

    Family and domain databases

    Gene3Di 3.30.470.20. 1 hit.
    3.40.50.7700. 1 hit.
    InterProi IPR013816. ATP_grasp_subdomain_2.
    IPR000031. PurE_dom.
    IPR028923. SAICAR_synt/ADE2_N.
    IPR018236. SAICAR_synthetase_CS.
    [Graphical view ]
    Pfami PF00731. AIRC. 1 hit.
    PF01259. SAICAR_synt. 1 hit.
    [Graphical view ]
    SMARTi SM01001. AIRC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52255. SSF52255. 1 hit.
    PROSITEi PS01057. SAICAR_SYNTHETASE_1. 1 hit.
    PS01058. SAICAR_SYNTHETASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Blast silkworm EST database for functional genes."
      Niu B.L., Meng Z.Q., Weng H.B., Shen W.F., He L.H., Zheng K.F., Ye S.T., Lin T.B., Chen J.E.
      Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "The genome of a lepidopteran model insect, the silkworm Bombyx mori."
      International Silkworm Genome Consortium
      Insect Biochem. Mol. Biol. 38:1036-1045(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: p50TImported.
    3. EnsemblMetazoa
      Submitted (DEC-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: p50T (Dazao)Imported.
    4. "Crystal structure of the invertebrate bifunctional purine biosynthesis enzyme PAICS at 2.8 A resolution."
      Taschner M., Basquin J., Benda C., Lorentzen E.
      Proteins 81:1473-1478(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS).

    Entry informationi

    Entry nameiQ1HQ66_BOMMO
    AccessioniPrimary (citable) accession number: Q1HQ66
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 13, 2006
    Last sequence update: June 13, 2006
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3