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Q1HQ66

- Q1HQ66_BOMMO

UniProt

Q1HQ66 - Q1HQ66_BOMMO

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Protein
Submitted name:

Phosphoribosylaminoimidazole carboxylase

Gene

LOC732910

Organism
Bombyx mori (Silk moth)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei20 – 201Sulfate 2; via amide nitrogen and carbonyl oxygenImported
Binding sitei93 – 931Sulfate 4Imported
Binding sitei93 – 931Sulfate 5Imported
Binding sitei104 – 1041Sulfate 6Imported
Binding sitei110 – 1101Sulfate 6Imported
Binding sitei145 – 1451Sulfate 7; via amide nitrogenImported
Binding sitei167 – 1671Sulfate 8Imported
Binding sitei205 – 2051Sulfate 8; via amide nitrogenImported
Binding sitei217 – 2171Sulfate 6Imported
Binding sitei332 – 3321Sulfate 10Imported
Binding sitei332 – 3321Sulfate 11Imported
Binding sitei332 – 3321Sulfate 9Imported
Binding sitei357 – 3571Sulfate 11Imported

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Source: InterPro

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphoribosylaminoimidazole carboxylaseImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:LOC732910Imported
OrganismiBombyx mori (Silk moth)
Taxonomic identifieri7091 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaLepidopteraGlossataDitrysiaBombycoideaBombycidaeBombycinaeBombyx
ProteomesiUP000005204: Unassembled WGS sequence

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JA0X-ray2.80A/B/C/D1-425[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni20 – 212Sulfate 1 bindingImported

Phylogenomic databases

KOiK01587.
OMAiTAFTRKC.
OrthoDBiEOG725DHT.

Family and domain databases

Gene3Di3.30.470.20. 1 hit.
3.40.50.7700. 1 hit.
InterProiIPR013816. ATP_grasp_subdomain_2.
IPR000031. PurE_dom.
IPR028923. SAICAR_synt/ADE2_N.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
PfamiPF00731. AIRC. 1 hit.
PF01259. SAICAR_synt. 1 hit.
[Graphical view]
SMARTiSM01001. AIRC. 1 hit.
[Graphical view]
SUPFAMiSSF52255. SSF52255. 1 hit.
PROSITEiPS01057. SAICAR_SYNTHETASE_1. 1 hit.
PS01058. SAICAR_SYNTHETASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1HQ66-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSHPKQVGQY KLGKLLIEGK TKQVFDVPDQ PGYCLLLNKD RITAGDGVKA
60 70 80 90 100
HDLEGKAAIS NQTNAKVFEI LKSAGIKTAF VKIASETAFL SKKCEMIPIE
110 120 130 140 150
WVTRRLATGS FLKRNPGVPE GFRFTPPKQE TFFKDDANHD PQWSEEQIIS
160 170 180 190 200
AKFNYNGLLI GRDEVDYMRK ATILIFEILE KAWALRDCAL IDMKIEFGVD
210 220 230 240 250
TEGSIVLADV IDSDSWRLWP SGDKRLMVDK QVYRNLTTVT AADLDTVKRN
260 270 280 290 300
FAWVKDQLDF LKPTIHHKVV VFMGSPADQE HCQKIAKAAR ELGLDVDLRV
310 320 330 340 350
TSAHKATEET LRIMQQYEDT HGALVFIAVA GRSNGLGPVL SGNTSYPVIN
360 370 380 390 400
CPPPSDKLVQ DIWSSLSVPS GLGCATVIYP DSAALMAAQI IGLQDYLVWG
410 420
RLRSKQLDMA HSLRQADKKL RNQTA
Length:425
Mass (Da):47,344
Last modified:June 13, 2006 - v1
Checksum:i245092F377D7EA1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF105371 Genomic DNA. No translation available.
DQ443186 mRNA. Translation: ABF51275.1.
RefSeqiNP_001040376.1. NM_001046911.1.
UniGeneiBmo.285.

Genome annotation databases

EnsemblMetazoaiBGIBMGA007935-RA; BGIBMGA007935-TA; BGIBMGA007935.
GeneIDi732910.
KEGGibmor:732910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF105371 Genomic DNA. No translation available.
DQ443186 mRNA. Translation: ABF51275.1 .
RefSeqi NP_001040376.1. NM_001046911.1.
UniGenei Bmo.285.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4JA0 X-ray 2.80 A/B/C/D 1-425 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai BGIBMGA007935-RA ; BGIBMGA007935-TA ; BGIBMGA007935 .
GeneIDi 732910.
KEGGi bmor:732910.

Phylogenomic databases

KOi K01587.
OMAi TAFTRKC.
OrthoDBi EOG725DHT.

Family and domain databases

Gene3Di 3.30.470.20. 1 hit.
3.40.50.7700. 1 hit.
InterProi IPR013816. ATP_grasp_subdomain_2.
IPR000031. PurE_dom.
IPR028923. SAICAR_synt/ADE2_N.
IPR018236. SAICAR_synthetase_CS.
[Graphical view ]
Pfami PF00731. AIRC. 1 hit.
PF01259. SAICAR_synt. 1 hit.
[Graphical view ]
SMARTi SM01001. AIRC. 1 hit.
[Graphical view ]
SUPFAMi SSF52255. SSF52255. 1 hit.
PROSITEi PS01057. SAICAR_SYNTHETASE_1. 1 hit.
PS01058. SAICAR_SYNTHETASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Blast silkworm EST database for functional genes."
    Niu B.L., Meng Z.Q., Weng H.B., Shen W.F., He L.H., Zheng K.F., Ye S.T., Lin T.B., Chen J.E.
    Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The genome of a lepidopteran model insect, the silkworm Bombyx mori."
    International Silkworm Genome Consortium
    Insect Biochem. Mol. Biol. 38:1036-1045(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: p50TImported.
  3. EnsemblMetazoa
    Submitted (DEC-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: p50T (Dazao)Imported.
  4. "Crystal structure of the invertebrate bifunctional purine biosynthesis enzyme PAICS at 2.8 A resolution."
    Taschner M., Basquin J., Benda C., Lorentzen E.
    Proteins 81:1473-1478(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS).

Entry informationi

Entry nameiQ1HQ66_BOMMO
AccessioniPrimary (citable) accession number: Q1HQ66
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2006
Last sequence update: June 13, 2006
Last modified: October 29, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3