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Protein

GDSL esterase/lipase 22

Gene

GLL22

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei43NucleophileBy similarity1
Active sitei322By similarity1
Active sitei325By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processLipid degradation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
GDSL esterase/lipase 22 (EC:3.1.1.-)
Alternative name(s):
Extracellular lipase At1g54000
GDSL esterase/lipase At1g54000
Gene namesi
Name:GLL22
Ordered Locus Names:At1g54000
ORF Names:F15I1.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G54000.
TAIRilocus:2014370. AT1G54000.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_000036736030 – 391GDSL esterase/lipase 22Add BLAST362

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi105N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi165N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi288N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ1H583.
PRIDEiQ1H583.

PTM databases

SwissPalmiQ1H583.

Expressioni

Gene expression databases

GenevisibleiQ1H583. AT.

Interactioni

Subunit structurei

Component of the PYK10 complex, at least composed of PYK10/BGLU23, BGLU21, BGLU22, JAL22, JAL23, PBP1/JAL30, PBP2/JAL31, JAL32, JAL33, JAL34, JAL35, GLL22 and GLL23.1 Publication

Protein-protein interaction databases

BioGridi27063. 1 interactor.
IntActiQ1H583. 1 interactor.
STRINGi3702.AT1G54000.1.

Structurei

3D structure databases

ProteinModelPortaliQ1H583.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 'GDSL' lipolytic enzyme family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JVXT. Eukaryota.
ENOG41105GE. LUCA.
HOGENOMiHOG000237649.
InParanoidiQ1H583.
OMAiCHEPLNN.
OrthoDBiEOG09360DDK.
PhylomeDBiQ1H583.

Family and domain databases

CDDicd01837. SGNH_plant_lipase_like. 1 hit.
Gene3Di3.40.50.1110. 1 hit.
InterProiView protein in InterPro
IPR001087. GDSL.
IPR036514. SGNH_hydro_sf.
IPR035669. SGNH_plant_lipase_like.
PfamiView protein in Pfam
PF00657. Lipase_GDSL. 1 hit.
SUPFAMiSSF52266. SSF52266. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q1H583-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMANNCNLVS VLCVILVLTL FHNPITVAGQ NSPVVALFTF GDSNFDAGNK
60 70 80 90 100
QTLTKTLVAQ GFWPYGKSRD DPNGKFSDGL ITPDFLAKFM KIPLAIAPAL
110 120 130 140 150
QPNVNVSRGA SFAVEGATLL GAPVESMTLN QQVKKFNQMK AANWNDDFVA
160 170 180 190 200
KSVFMIYIGA NDYLNFTKNN PTADASAQQA FVTSVTNKLK NDISALYSSG
210 220 230 240 250
ASKFVIQTLA PLGCLPIVRQ EYNTGMDQCY EKLNDLAKQH NEKIGPMLNE
260 270 280 290 300
MARNSPASAP FQFTVFDFYN AVLTRTQRNQ NFRFFVTNAS CCGVGSHDAY
310 320 330 340 350
GCGLPNVHSK LCEYQRSFLF FDGRHNSEKA QEMFAHLLFG ADTNVVQPMN
360 370 380 390
VRELTVYPVD EPMREFWVPP TPATVHASDS SSSTSRGYEY Y
Length:391
Mass (Da):43,194
Last modified:June 27, 2006 - v1
Checksum:i01F562BAE8F5A467
GO

Sequence cautioni

The sequence AAD25772 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAM64922 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti15I → F in AAM64922 (Ref. 4) Curated1
Sequence conflicti191N → S in AAM64922 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006577 Genomic DNA. Translation: AAD25772.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE33033.1.
BT025581 mRNA. Translation: ABF58999.1.
AY087372 mRNA. Translation: AAM64922.1. Different initiation.
PIRiE96580.
RefSeqiNP_175802.1. NM_104277.4.
UniGeneiAt.23298.

Genome annotation databases

EnsemblPlantsiAT1G54000.1; AT1G54000.1; AT1G54000.
GeneIDi841838.
GrameneiAT1G54000.1; AT1G54000.1; AT1G54000.
KEGGiath:AT1G54000.

Similar proteinsi

Entry informationi

Entry nameiGDL18_ARATH
AccessioniPrimary (citable) accession number: Q1H583
Secondary accession number(s): Q8LB78, Q9SYF6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 27, 2006
Last modified: October 25, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families