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Q1H4R7 (Q1H4R7_METFK) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase 1 HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023
Alternative name(s):
Imidazole acetol-phosphate transaminase 1 HAMAP MF_01023
Gene names
Name:hisC1 HAMAP MF_01023
Ordered Locus Names:Mfla_0249
OrganismMethylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) [Complete proteome] [HAMAP] EMBL ABE48520.1
Taxonomic identifier265072 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Methylophilales › Methylophilaceae › Methylobacillus

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861

Subunit structure

Homodimer By similarity. HAMAP MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2101N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

Sequence LengthMass (Da)Tools
Q1H4R7 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: 006C705A58B1379E

FASTA35438,981
        10         20         30         40         50         60 
MSKFWSAIVH ELTPYVPGEQ PKLTNLVKLN TNENPYGPSP KVLAALEAEV ADSLRLYPDP 

        70         80         90        100        110        120 
TSAKLVQAVA KFYNVPATHV FVGNGSDEVL AHTFQALLKH DQPILFPDIT YSFYPVYCGL 

       130        140        150        160        170        180 
YGIEYQTIAL NDEFQIDVSD YKRPNGGIIF PNPNAPTGCG LPLAEIERLL EVNTESVVVV 

       190        200        210        220        230        240 
DEAYVDFGAE SVVGLVARYP NLLVTHTMSK ARSLAGLRVG YAIGQPPLIE ALTRVKDSFN 

       250        260        270        280        290        300 
SYPLDRFAIS GATAAIEDKA YFEETCRKVV ATRQALVREL QALGFFVLPS VANFIFARHG 

       310        320        330        340        350 
KRSGDELAAS LRARNIIVRH FSKPARISDF LRITIGTDVQ SQALVEALKD ILIH

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References

[1]"Complete sequence of Methylobacillus flagellatus KT."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Kyrpides N., Anderson I., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KT / ATCC 51484 / DSM 6875.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000284 Genomic DNA. Translation: ABE48520.1.
RefSeqYP_544361.1. NC_007947.1.

3D structure databases

ProteinModelPortalQ1H4R7.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1H4R7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3999434.
GenomeReviewsGene locus Mfla_0249 in contig CP000284_GR.
KEGGmfa:Mfla_0249.
NMPDRfig|265072.7.peg.251.
PATRIC32266013. VBIMetFla97085_0254.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0079.
HOGENOMHBG646350.
OMAMKNSFNS.
PhylomeDBQ1H4R7.
ProtClustDBPRK05387.

Family and domain databases

HAMAPMF_01023. HisC_aminotrans_2.
[Tree]
InterProIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00817.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01141. HisC. 1 hit.
PROSITEPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1H4R7_METFK
AccessionPrimary (citable) accession number: Q1H4R7
Entry history
Integrated into UniProtKB/TrEMBL: June 27, 2006
Last sequence update: June 27, 2006
Last modified: December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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