Q1H395 (Q1H395_METFK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361
Short name=Poly(P)/ATP NAD kinase HAMAP MF_00361
EC=2.7.1.23 HAMAP MF_00361

Gene names

Name:	ppnK HAMAP MF_00361
Ordered Locus Names:	Mfla_0774

Organism

Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) [Complete proteome] [HAMAP] EMBL ABE49042.1

Taxonomic identifier

265072 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Methylophilales › Methylophilaceae › Methylobacillus

Protein attributes

Sequence length	290 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361
Subcellular location	Cytoplasm By similarity HAMAP MF_00361.
Sequence similarities	Belongs to the NAD kinase family. HAMAP MF_00361

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00361
Ligand	ATP-binding HAMAP MF_00361 NAD HAMAP MF_00361 NADP HAMAP MF_00361 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00361 EMBL ABE49042.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1H395 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: F115CA76729BBEA4	FASTA	290	31,587
	10 20 30 40 50 60 MPAMKSAFQT VALIGKYMNP ETREQILSLA RFLGERHIGV FIEEKTAQHS SIKGYTTLQM 70 80 90 100 110 120 NAIGAYADLA IVLGGDGTML TVARALVDYK IPLVGVNRGR FGFLTDINSD HMLESVAAIL 130 140 150 160 170 180 DGMFDTEQRI LLEACIVREG RTVAQGYALN DVVVNKNGLA RLIELEIHID GHFVQRQRSD 190 200 210 220 230 240 GLIVATPTGT TAYSLSAGGP ILYPTLDAIA LVPICPHTLS NRPIAISSAS QVSIQVVHAE 250 260 270 280 290 DASVHLDGQM KMALQPGDHV QVKRAKNTIT LLHPPGHNHY DVLREKLHWG

References

[1]

"Complete sequence of Methylobacillus flagellatus KT." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J. , Larimer F., Land M., Kyrpides N., Anderson I., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KT / ATCC 51484 / DSM 6875.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000284 Genomic DNA. Translation: ABE49042.1.
RefSeq	YP_544883.1. NC_007947.1.
3D structure databases
ProteinModelPortal	Q1H395.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1H395.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4000630.
GenomeReviews	Gene locus Mfla_0774 in contig CP000284_GR.
KEGG	mfa:Mfla_0774.
NMPDR	fig|265072.7.peg.776.
PATRIC	32267135. VBIMetFla97085_0805.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0061.
HOGENOM	HBG713904.
OMA	TGSTCYT.
PhylomeDB	Q1H395.
ProtClustDB	CLSK2529292.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1H395_METFK

Accession

Primary (citable) accession number: Q1H395

Entry history

Integrated into UniProtKB/TrEMBL:	June 27, 2006
Last sequence update:	June 27, 2006
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)