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Q1H1P4

- G6PI_METFK

UniProt

Q1H1P4 - G6PI_METFK

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Protein

Glucose-6-phosphate isomerase

Gene
pgi, Mfla_1325
Organism
Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei353 – 3531Proton donor By similarity
Active sitei384 – 3841 By similarity
Active sitei516 – 5161 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciMFLA265072:GHWJ-1355-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:Mfla_1325
OrganismiMethylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)
Taxonomic identifieri265072 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaMethylophilalesMethylophilaceaeMethylobacillus
ProteomesiUP000002440: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 555555Glucose-6-phosphate isomeraseUniRule annotationPRO_0000252630Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi265072.Mfla_1325.

Structurei

3D structure databases

ProteinModelPortaliQ1H1P4.
SMRiQ1H1P4. Positions 5-552.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1H1P4-1 [UniParc]FASTAAdd to Basket

« Hide

MTNPTNCPIW HDLSAHYQEV LPLQMRDMFT KDGRRFEKFS LEAEGLLLDY    50
SKHRITDETL PLLFKLARDS KVEEWRDRMF AGEKINFTEN RAVLHTALRN 100
RSNTPVYVDG KDVMPDVNRV LAQMRKFSTS IRSGEWKGYS GKRITDVVNI 150
GIGGSDLGPV MVCGALKPYA QAGLNAHFVS NIDGTHLAQT LERCDPETTL 200
FIVASKTFTT QETMTNARSA RSWFLQAAKD EAHVAKHFVA ISTNADEVGK 250
FGIDAANMFE FWDWVGGRYS LWSAIGLSIA IYIGMDHFEE LLQGGYEIDR 300
HFKNAPLEQN IPVIMALLGI WYNNFFGADS LAILPYDQGL ARFPAYLQQA 350
DMESNGKFVA RDGRIVQCTT GPIIWGEAGT NGQHAFYQLI HQGNRLIPCD 400
FMMPLQSHYS MGKNGNEHHL ILLANCFAQT SALMQGKTLD EAKAELVAQG 450
LTGEALETLL PHKVFEGNRP STTILFDKLT PKTLGKLIAI YEHKIFVQGI 500
IWNINSFDQW GVEYGKQIAK KILPQLSEDQ ASTEYDSSTN GLMNYFKSRT 550
QSSGT 555
Length:555
Mass (Da):62,321
Last modified:October 17, 2006 - v2
Checksum:iC2A8DA65993DB616
GO

Sequence cautioni

The sequence ABE49593.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000284 Genomic DNA. Translation: ABE49593.1. Different initiation.
RefSeqiYP_545434.1. NC_007947.1.

Genome annotation databases

EnsemblBacteriaiABE49593; ABE49593; Mfla_1325.
GeneIDi4000036.
KEGGimfa:Mfla_1325.
PATRICi32268357. VBIMetFla97085_1411.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000284 Genomic DNA. Translation: ABE49593.1 . Different initiation.
RefSeqi YP_545434.1. NC_007947.1.

3D structure databases

ProteinModelPortali Q1H1P4.
SMRi Q1H1P4. Positions 5-552.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 265072.Mfla_1325.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE49593 ; ABE49593 ; Mfla_1325 .
GeneIDi 4000036.
KEGGi mfa:Mfla_1325.
PATRICi 32268357. VBIMetFla97085_1411.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci MFLA265072:GHWJ-1355-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KT / ATCC 51484 / DSM 6875.

Entry informationi

Entry nameiG6PI_METFK
AccessioniPrimary (citable) accession number: Q1H1P4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: October 17, 2006
Last modified: June 11, 2014
This is version 49 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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