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Q1H1P4

- G6PI_METFK

UniProt

Q1H1P4 - G6PI_METFK

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 2 (17 Oct 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei353 – 3531Proton donorUniRule annotation
    Active sitei384 – 3841UniRule annotation
    Active sitei516 – 5161UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciMFLA265072:GHWJ-1355-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:Mfla_1325
    OrganismiMethylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)
    Taxonomic identifieri265072 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaMethylophilalesMethylophilaceaeMethylobacillus
    ProteomesiUP000002440: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 555555Glucose-6-phosphate isomerasePRO_0000252630Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi265072.Mfla_1325.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1H1P4.
    SMRiQ1H1P4. Positions 5-552.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261370.
    KOiK01810.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1H1P4-1 [UniParc]FASTAAdd to Basket

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    MTNPTNCPIW HDLSAHYQEV LPLQMRDMFT KDGRRFEKFS LEAEGLLLDY    50
    SKHRITDETL PLLFKLARDS KVEEWRDRMF AGEKINFTEN RAVLHTALRN 100
    RSNTPVYVDG KDVMPDVNRV LAQMRKFSTS IRSGEWKGYS GKRITDVVNI 150
    GIGGSDLGPV MVCGALKPYA QAGLNAHFVS NIDGTHLAQT LERCDPETTL 200
    FIVASKTFTT QETMTNARSA RSWFLQAAKD EAHVAKHFVA ISTNADEVGK 250
    FGIDAANMFE FWDWVGGRYS LWSAIGLSIA IYIGMDHFEE LLQGGYEIDR 300
    HFKNAPLEQN IPVIMALLGI WYNNFFGADS LAILPYDQGL ARFPAYLQQA 350
    DMESNGKFVA RDGRIVQCTT GPIIWGEAGT NGQHAFYQLI HQGNRLIPCD 400
    FMMPLQSHYS MGKNGNEHHL ILLANCFAQT SALMQGKTLD EAKAELVAQG 450
    LTGEALETLL PHKVFEGNRP STTILFDKLT PKTLGKLIAI YEHKIFVQGI 500
    IWNINSFDQW GVEYGKQIAK KILPQLSEDQ ASTEYDSSTN GLMNYFKSRT 550
    QSSGT 555
    Length:555
    Mass (Da):62,321
    Last modified:October 17, 2006 - v2
    Checksum:iC2A8DA65993DB616
    GO

    Sequence cautioni

    The sequence ABE49593.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000284 Genomic DNA. Translation: ABE49593.1. Different initiation.
    RefSeqiYP_545434.1. NC_007947.1.

    Genome annotation databases

    EnsemblBacteriaiABE49593; ABE49593; Mfla_1325.
    GeneIDi4000036.
    KEGGimfa:Mfla_1325.
    PATRICi32268357. VBIMetFla97085_1411.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000284 Genomic DNA. Translation: ABE49593.1 . Different initiation.
    RefSeqi YP_545434.1. NC_007947.1.

    3D structure databases

    ProteinModelPortali Q1H1P4.
    SMRi Q1H1P4. Positions 5-552.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 265072.Mfla_1325.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE49593 ; ABE49593 ; Mfla_1325 .
    GeneIDi 4000036.
    KEGGi mfa:Mfla_1325.
    PATRICi 32268357. VBIMetFla97085_1411.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261370.
    KOi K01810.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci MFLA265072:GHWJ-1355-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KT / ATCC 51484 / DSM 6875.

    Entry informationi

    Entry nameiG6PI_METFK
    AccessioniPrimary (citable) accession number: Q1H1P4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 17, 2006
    Last sequence update: October 17, 2006
    Last modified: October 1, 2014
    This is version 50 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3