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Q1H0N7 (Q1H0N7_METFK) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroloquinoline-quinone synthase HAMAP MF_00654
EC=1.3.3.11 HAMAP MF_00654
Alternative name(s):
Coenzyme PQQ synthesis protein C HAMAP MF_00654
Pyrroloquinoline quinone biosynthesis protein C HAMAP MF_00654
Gene names
Name:pqqC HAMAP MF_00654
Ordered Locus Names:Mfla_1682
OrganismMethylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) [Complete proteome] [HAMAP] EMBL ABE49950.1
Taxonomic identifier265072 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Methylophilales › Methylophilaceae › Methylobacillus

Protein attributes

Sequence length250 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family. HAMAP MF_00654

Ontologies

Keywords
   Biological processPQQ biosynthesis HAMAP MF_00654
   Molecular functionOxidoreductase HAMAP MF_00654
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q1H0N7 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: 3524E7BF92A6BBC6

FASTA25029,170
        10         20         30         40         50         60 
MNAPLTDNIP WTREEFEQKL RDKGRGYHIY HPFHVMMYEG KLTREQLQCW VANRFYYQIS 

        70         80         90        100        110        120 
IPQKDAAILS NCPDKEIRKG WIQRIIDHDG DANNVGGIEA WIQLGQAVGL SREDVTSLKF 

       130        140        150        160        170        180 
VAPGVRFAVD AYVNFAKQRP WQEAVCSSLT ELFAPHIHQQ RISSWPSMYP WVKEEGLTYF 

       190        200        210        220        230        240 
KKRLTEARRD VEQGLAVTLD YFSQSRELQE KALDILQFKL DVLWVIADAI MLASTNIKVE 

       250 
QHVDYLRQPR

« Hide

References

[1]"Complete sequence of Methylobacillus flagellatus KT."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Kyrpides N., Anderson I., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KT / ATCC 51484 / DSM 6875.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000284 Genomic DNA. Translation: ABE49950.1.
RefSeqYP_545791.1. NC_007947.1.

3D structure databases

ProteinModelPortalQ1H0N7.
SMRQ1H0N7. Positions 14-233.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1H0N7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4000937.
GenomeReviewsGene locus Mfla_1682 in contig CP000284_GR.
KEGGmfa:Mfla_1682.
NMPDRfig|265072.7.peg.1706.
PATRIC32269115. VBIMetFla97085_1781.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG5424.
HOGENOMHBG288944.
OMADSWPQHY.
ProtClustDBPRK05157.

Family and domain databases

HAMAPMF_00654. PQQ_syn_PqqC.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synthPqqC_dom.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KOK06137.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMSSF48613. Heme_oxygenase. 1 hit.
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ1H0N7_METFK
AccessionPrimary (citable) accession number: Q1H0N7
Entry history
Integrated into UniProtKB/TrEMBL: June 27, 2006
Last sequence update: June 27, 2006
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info