ID   Q1GZY7_METFK            Unreviewed;       598 AA.
AC   Q1GZY7;
DT   27-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   27-JUN-2006, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor {ECO:0000313|EMBL:ABE50200.1};
GN   OrderedLocusNames=Mfla_1933 {ECO:0000313|EMBL:ABE50200.1};
OS   Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Methylophilaceae; Methylobacillus.
OX   NCBI_TaxID=265072 {ECO:0000313|EMBL:ABE50200.1, ECO:0000313|Proteomes:UP000002440};
RN   [1] {ECO:0000313|EMBL:ABE50200.1, ECO:0000313|Proteomes:UP000002440}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KT / ATCC 51484 / DSM 6875 {ECO:0000313|Proteomes:UP000002440};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Anderson I., Richardson P.;
RT   "Complete sequence of Methylobacillus flagellatus KT.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000284; ABE50200.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q1GZY7; -.
DR   STRING; 265072.Mfla_1933; -.
DR   KEGG; mfa:Mfla_1933; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_26_4; -.
DR   Proteomes; UP000002440; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002440};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        169..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          25..60
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          216..268
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          273..502
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          288..308
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          519..598
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          473..511
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   598 AA;  64399 MW;  326592A4203B7E46 CRC64;
     MRINMPVTNN EYFLQDGQSI LSTTDLQGKI TYINQDFIEV SGFTEDELIG SPHNLVRHPD
     MPPEAFADMW ATLKAGLPWT GMVKNRRKNG DYYWVLANAT PMRQNGNVVG YMSVRVKPSR
     QQVEQASQIY ARLRENKHHG LKLHRGEILK TDFISRVRRA MQMTLKTQVA VTTIAILLAM
     VVVIAATFNG LDISFVVGGA LVAMVAMLSL AVSLSNSVIK PLREATDIAN ALASGDLSHK
     FSASKTDETG MLLRALNQMN VNIVAMITDI RTNMQRINTG VNEIANGNND LSARTESQAS
     SLEETASSME ELASTVKQNA DNARQANQLV ISASSVAARG GEVIGEVRDR MRLISESANK
     ISDIIGVIDG IAFQTNILAL NAAVEAARAG EQGRGFAVVA SEVRNLAHRS AAAAKEIKGL
     ISDSVERVEA GVEFVDQAGT TMTEIVASVR NVTDIMAEIS AASIEQSAGI DQVNHAVNDM
     DEVTQRNAAL VEESAAAADA LRQDVLQLER AASVFKLGNG RDTPLERDPR AQAKESAPET
     PPSKVKADVV SSASAKQRVS VAKVNAKPAA IPNATPSRSG IHKKVVGSDL SSDEWEEF
//