Reviewed, UniProtKB/Swiss-Prot Q1GXL1 (MQO_METFK)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	Mfla_0011

Organism

Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) [Complete proteome] [HAMAP]

Taxonomic identifier

265072 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Methylophilales › Methylophilaceae › Methylobacillus

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor.
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 492	492	Probable malate:quinone oxidoreductase		PRO_0000325499

Sequences

	Sequence		Length	Mass (Da)
	Q1GXL1-1 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: F88AE0F979A814B2	FASTA	492	53,861
	10 20 30 40 50 60 MTSSLDTDIL LVGGGIMSAT LGTLLHQLNP ELRITLVELQ AEVATESSDG WNNAGTGHAG 70 80 90 100 110 120 YCELNYTPQD ADGSVPIARA LKINAAFEES LQFWAWLVEK GILREPASFI NPTPHSSFVW 130 140 150 160 170 180 GEKNVAFLRK RHQALRAHHL FADMEYSQDP AVLQQWMPLV MAGRDPSIPV AATRVAYGSD 190 200 210 220 230 240 VDFGSLTRQL VQHLQGRPGF KLLTRHAVTG LKQQGSWQVK AVDLSQGKPV EIRAGFVFLG 250 260 270 280 290 300 AGGATLPLLQ KSAIQEARGY GGFPVSGQWL VCHNPDVIHQ HHAKVYGKAP LGAPPMSVPH 310 320 330 340 350 360 LDTRIINGKP ALLFGPFAGF TTRFLKRGSL LDLVNSVKRS NLKSMLGAGR HHMDLTRYLI 370 380 390 400 410 420 GEVFQSHQQR MAALRNFYPL ANESEWSLVS AGQRVQIIKQ CEHQGGKLEF GTEIVSSADG 430 440 450 460 470 480 SLAALLGASP GASTSVPAML EVLQRCFSPQ LQSAAWQERM REMLPSYGQS LIEDAELLRA 490 VRYHTLSRLK LT

References

[1]

"Complete sequence of Methylobacillus flagellatus KT." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J. , Larimer F., Land M., Kyrpides N., Anderson I., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000284 Genomic DNA. Translation: ABE48282.1.
RefSeq	YP_544123.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3999693.
GenomeReviews	Gene locus Mfla_0011 in contig CP000284_GR.
KEGG	mfa:Mfla_0011.
NMPDR	fig|265072.7.peg.12.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1GXL1.
Enzyme and pathway databases
BioCyc	MFLA265072:MFLA_0011-MON.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_METFK

Accession

Primary (citable) accession number: Q1GXL1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	June 27, 2006
Last modified:	November 4, 2008
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)