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Q1GXL1 (MQO_METFK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:Mfla_0011
OrganismMethylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) [Complete proteome] [HAMAP]
Taxonomic identifier265072 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Methylophilales › Methylophilaceae › Methylobacillus

Protein attributes

Sequence length492 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 492492Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_0000325499

Sequences

Sequence LengthMass (Da)Tools
Q1GXL1 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: F88AE0F979A814B2

FASTA49253,861
        10         20         30         40         50         60 
MTSSLDTDIL LVGGGIMSAT LGTLLHQLNP ELRITLVELQ AEVATESSDG WNNAGTGHAG 

        70         80         90        100        110        120 
YCELNYTPQD ADGSVPIARA LKINAAFEES LQFWAWLVEK GILREPASFI NPTPHSSFVW 

       130        140        150        160        170        180 
GEKNVAFLRK RHQALRAHHL FADMEYSQDP AVLQQWMPLV MAGRDPSIPV AATRVAYGSD 

       190        200        210        220        230        240 
VDFGSLTRQL VQHLQGRPGF KLLTRHAVTG LKQQGSWQVK AVDLSQGKPV EIRAGFVFLG 

       250        260        270        280        290        300 
AGGATLPLLQ KSAIQEARGY GGFPVSGQWL VCHNPDVIHQ HHAKVYGKAP LGAPPMSVPH 

       310        320        330        340        350        360 
LDTRIINGKP ALLFGPFAGF TTRFLKRGSL LDLVNSVKRS NLKSMLGAGR HHMDLTRYLI 

       370        380        390        400        410        420 
GEVFQSHQQR MAALRNFYPL ANESEWSLVS AGQRVQIIKQ CEHQGGKLEF GTEIVSSADG 

       430        440        450        460        470        480 
SLAALLGASP GASTSVPAML EVLQRCFSPQ LQSAAWQERM REMLPSYGQS LIEDAELLRA 

       490 
VRYHTLSRLK LT

« Hide

References

[1]"Complete sequence of Methylobacillus flagellatus KT."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Kyrpides N., Anderson I., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KT / ATCC 51484 / DSM 6875.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000284 Genomic DNA. Translation: ABE48282.1.
RefSeqYP_544123.1. NC_007947.1.

3D structure databases

ProteinModelPortalQ1GXL1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1GXL1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3999693.
GenomeReviewsGene locus Mfla_0011 in contig CP000284_GR.
KEGGmfa:Mfla_0011.
NMPDRfig|265072.7.peg.12.
PATRIC32265511. VBIMetFla97085_0012.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
HOGENOMHBG289663.
OMANTQFEVS.
PhylomeDBQ1GXL1.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycMFLA265072:MFLA_0011-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_METFK
AccessionPrimary (citable) accession number: Q1GXL1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: June 27, 2006
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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