Q1GXK9 (Q1GXK9_METFK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
EC=1.8.4.12 HAMAP MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP MF_01400

Gene names

Name:	msrB HAMAP MF_01400
Ordered Locus Names:	Mfla_0013

Organism

Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) [Complete proteome] [HAMAP] EMBL ABE48284.1

Taxonomic identifier

265072 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Methylophilales › Methylophilaceae › Methylobacillus

Protein attributes

Sequence length	130 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP MF_01400

Ontologies

Keywords
Ligand	Metal-binding HAMAP MF_01400 Zinc HAMAP MF_01400
Molecular function	Oxidoreductase HAMAP MF_01400 SAAS SAAS002579 EMBL ABE48284.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	119	1	Nucleophile By similarity HAMAP MF_01400
	Metal binding	47	1	Zinc By similarity HAMAP MF_01400
	Metal binding	50	1	Zinc By similarity HAMAP MF_01400
	Metal binding	96	1	Zinc By similarity HAMAP MF_01400
	Metal binding	99	1	Zinc By similarity HAMAP MF_01400

Sequences

	Sequence		Length	Mass (Da)
	Q1GXK9 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: A3862F72F87243B3	FASTA	130	14,616
	10 20 30 40 50 60 MTKVFKTDAE WREQLTPLQY EVTRHAATER AGTGEYAFHF EHGIYHCVCC GTPLFASDTK 70 80 90 100 110 120 FDAGCGWPSY FEALDPDNIR EKADYAYGMV RTEVICNVCD AHLGHVFPDG PPPTGLRYCI 130 NSASLRFEPS

References

[1]

"Complete sequence of Methylobacillus flagellatus KT." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J. , Larimer F., Land M., Kyrpides N., Anderson I., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KT / ATCC 51484 / DSM 6875.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000284 Genomic DNA. Translation: ABE48284.1.
RefSeq	YP_544125.1. NC_007947.1.
3D structure databases
ProteinModelPortal	Q1GXK9.
SMR	Q1GXK9. Positions 6-128.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1GXK9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3999695.
GenomeReviews	Gene locus Mfla_0013 in contig CP000284_GR.
KEGG	mfa:Mfla_0013.
NMPDR	fig|265072.7.peg.14.
PATRIC	32265515. VBIMetFla97085_0014.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0229.
HOGENOM	HBG715255.
OMA	LFESATK.
PhylomeDB	Q1GXK9.
ProtClustDB	CLSK2529028.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1GXK9_METFK

Accession

Primary (citable) accession number: Q1GXK9

Entry history

Integrated into UniProtKB/TrEMBL:	June 27, 2006
Last sequence update:	June 27, 2006
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)