Q1GWG9 (ACP_SPHAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acyl carrier protein
Short name=ACP

Gene names

Name:	acpP
Ordered Locus Names:	Sala_0280

Organism

Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis) [Complete proteome] [HAMAP]

Taxonomic identifier

317655 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Sphingopyxis

Protein attributes

Sequence length	78 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Carrier of the growing fatty acid chain in fatty acid biosynthesis By similarity. HAMAP MF_01217
Pathway	Lipid metabolism; fatty acid biosynthesis. HAMAP MF_01217
Subcellular location	Cytoplasm By similarity HAMAP MF_01217.
Post-translational modification	4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group By similarity. HAMAP MF_01217
Sequence similarities	Contains 1 acyl carrier domain.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Ligand	Phosphopantetheine
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 78	78	Acyl carrier protein HAMAP MF_01217		PRO_1000066696
Amino acid modifications
	Modified residue	37	1	O-(pantetheine 4'-phosphoryl)serine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1GWG9 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: 2FD473DC3F958702	FASTA	78	8,457
	10 20 30 40 50 60 MSDSAEKVKK IVVEHLGVEA DKVTEEASFI DDLGADSLDI VELVMAFEEE FGVEIPDDAA 70 EKIATVKDAI DYIEANKG

References

[1]

"Complete sequence of chromosome of Sphingopyxis alaskensis RB2256." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Chertkov O., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Cavicchioli R., Robb F., Ertan H., Schut F., Ting L.M., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13593 / LMG 18877 / RB2256.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000356 Genomic DNA. Translation: ABF52003.1.
RefSeq	YP_615336.1. NC_008048.1.
3D structure databases
ProteinModelPortal	Q1GWG9.
SMR	Q1GWG9. Positions 6-78.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4082640.
GenomeReviews	Gene locus Sala_0280 in contig CP000356_GR.
KEGG	sal:Sala_0280.
NMPDR	fig|317655.9.peg.255.
PATRIC	23689699. VBISphAla23391_0299.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG755218.
OMA	PESRFTE.
ProtClustDB	PRK00982.
Enzyme and pathway databases
BioCyc	SALA317655:SALA_0280-MONOMER.
Family and domain databases
HAMAP	MF_01217. Acyl_carrier. [Tree]
InterPro	IPR003231. Acyl_carrier. IPR009081. Acyl_carrier_prot-like. IPR006163. Phsphopanteth-bd. IPR006162. PPantetheine_attach_site. [Graphical view]
Gene3D	G3DSA:1.10.1200.10. ACP_like. 1 hit.
KO	K02078.
Pfam	PF00550. PP-binding. 1 hit. [Graphical view]
ProDom	PD000887. PD000887. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF47336. ACP_like. 1 hit.
TIGRFAMs	TIGR00517. Acyl_carrier. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACP_SPHAL

Accession

Primary (citable) accession number: Q1GWG9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	June 27, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program