ID   Q1GW96_SPHAL            Unreviewed;       699 AA.
AC   Q1GW96;
DT   27-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   27-JUN-2006, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ABF52076.1};
GN   OrderedLocusNames=Sala_0353 {ECO:0000313|EMBL:ABF52076.1};
OS   Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256)
OS   (Sphingomonas alaskensis).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingopyxis.
OX   NCBI_TaxID=317655 {ECO:0000313|EMBL:ABF52076.1, ECO:0000313|Proteomes:UP000006578};
RN   [1] {ECO:0000313|EMBL:ABF52076.1, ECO:0000313|Proteomes:UP000006578}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13593 / LMG 18877 / RB2256
RC   {ECO:0000313|Proteomes:UP000006578};
RX   PubMed=19805210; DOI=10.1073/pnas.0903507106;
RA   Lauro F.M., McDougald D., Thomas T., Williams T.J., Egan S., Rice S.,
RA   DeMaere M.Z., Ting L., Ertan H., Johnson J., Ferriera S., Lapidus A.,
RA   Anderson I., Kyrpides N., Munk A.C., Detter C., Han C.S., Brown M.V.,
RA   Robb F.T., Kjelleberg S., Cavicchioli R.;
RT   "The genomic basis of trophic strategy in marine bacteria.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:15527-15533(2009).
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DR   EMBL; CP000356; ABF52076.1; -; Genomic_DNA.
DR   RefSeq; WP_011540667.1; NC_008048.1.
DR   AlphaFoldDB; Q1GW96; -.
DR   STRING; 317655.Sala_0353; -.
DR   KEGG; sal:Sala_0353; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG4252; Bacteria.
DR   HOGENOM; CLU_000445_85_1_5; -.
DR   OrthoDB; 9789782at2; -.
DR   Proteomes; UP000006578; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006578};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        44..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        337..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        365..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        396..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          458..591
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   699 AA;  75586 MW;  6DF78CADE01636C1 CRC64;
     MNAPETPVRA AEAVTPDDAD GRPPTVPLAK RVRRLVTQLG PSRMVATILF LVLAVLIARF
     SWQMPLINAA ERALYDARAT LMAPKVQQDP RILLVTYNDE TLFNTGIRSP LDRSLLTAAL
     ANIDQMGAKA IGIDIAFDSP RPDDAALKAQ LRAMQTPTWL AYAEQASNPN TIFYEQQKFL
     ESFIADVATA RTRPTSVLFH TDDDSVIRRW PDRPAGLPPL MANALAPVDP AHAGYRGAIR
     FLVPARAGGG QVEPVFANIP IDSFALPMDA AMRAGFSELV KDRYVLIGGD IIDNDQFNTP
     LSRFPDAITG QHETMIGLEV HAHMLAQQLD GAWARPLAGP TLWVLALLVV LAGGLTSLID
     MRARWVALAF LGQMAFFVAF PFWLQGRGID TTTLPTFGWA VGWLFGYAAV GTAARTIGSR
     QRAFAQSALG KYLPADVAEQ IMRDPDQLSL HGERRNIFCV FTDLEGFTKL SHAVTPETVA
     RLLNEYLDRL SDIVLAHGGT IDKFVGDAVV AFWGAPISRP DDGEKAATAA LAMYQAGERF
     RVDLAAGDIP PIGMTRVGLH VGDAIVGNFG GEGRIQYTAL GDSMNTASRL EAANKSLKTG
     VLISAEAAAR SGRDDLVPMG RVTLRGRAQP VDVFTPRPDL APDQRGRIAA LVAAHGAGDN
     DACVTLATEL AQELRQDAAI QFLIERLNQT KRGESYVLS
//